{"id":31429,"date":"2024-01-02T13:01:12","date_gmt":"2024-01-02T13:01:12","guid":{"rendered":"https:\/\/amelie-project.eu\/?p=31429"},"modified":"2024-01-02T13:02:51","modified_gmt":"2024-01-02T13:02:51","slug":"destaque-para-a-incontinencia-fecal-no-journal-of-cell-and-gene-therapy-insights","status":"publish","type":"post","link":"https:\/\/amelie-project.eu\/pt\/destaque-para-a-incontinencia-fecal-no-journal-of-cell-and-gene-therapy-insights\/","title":{"rendered":"Destaque para a incontin\u00eancia fecal no Journal of Cell and Gene Therapy Insights"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_row _builder_version=&#8221;4.21.0&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221; width=&#8221;100%&#8221; sticky_enabled=&#8221;0&#8243;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<!-- divi:paragraph --><\/p>\n<p>As causas e os impactos da incontin\u00eancia fecal est\u00e3o a ser destacados na \u00faltima edi\u00e7\u00e3o do Journal of Cell and Gene Therapy Insights. A les\u00e3o do esf\u00edncter \u00e9 uma das principais causas da incontin\u00eancia fecal, e este artigo explora a forma como as tecnologias inovadoras, como a terapia celular, podem alterar o panorama do tratamento destes doentes carenciados.<\/p>\n<p>Leia um extrato do artigo aqui:<\/p>\n<p><!-- divi:paragraph --><\/p>\n<p style=\"padding-left: 40px\"><em>A incontin\u00eancia fecal \u00e9 uma doen\u00e7a prevalente, que continua a ser muito subnotificada. Esta doen\u00e7a afecta a qualidade de vida dos doentes e tem um impacto socioecon\u00f3mico e ambiental negativo na sociedade. As actuais diretrizes de gest\u00e3o de doentes recomendam uma abordagem faseada para o tratamento da incontin\u00eancia fecal, desde op\u00e7\u00f5es de tratamento conservadoras, passando por op\u00e7\u00f5es cir\u00fargicas minimamente invasivas, at\u00e9 op\u00e7\u00f5es cir\u00fargicas de primeira e segunda linha. Infelizmente, os tratamentos conservadores continuam a ser ineficazes e, em muitos casos, as op\u00e7\u00f5es cir\u00fargicas n\u00e3o s\u00e3o desej\u00e1veis ou n\u00e3o s\u00e3o adequadas. A medicina regenerativa e, especificamente, a terapia celular, tem o potencial de oferecer um tratamento curativo que \u00e9 menos invasivo, mais eficaz e eficiente. As tecnologias de terapia celular, embora ainda em desenvolvimento, podem melhorar a situa\u00e7\u00e3o atual no dom\u00ednio da incontin\u00eancia fecal a n\u00edvel cl\u00ednico, do doente e socioecon\u00f3mico. O objetivo deste artigo \u00e9 duplo. Em primeiro lugar, \u00e9 sensibilizar para o problema silencioso que \u00e9 a incontin\u00eancia fecal e para o impacto que tem nos doentes e na sociedade. Em segundo lugar, pretende-se posicionar a terapia celular em rela\u00e7\u00e3o \u00e0s abordagens de tratamento actuais, incluindo, por exemplo, a estimula\u00e7\u00e3o do nervo sacral e a esfincteroplastia, de modo a real\u00e7ar o seu potencial para proporcionar uma alternativa de tratamento adequada.<\/em><\/p>\n<p>\u00a0Para aceder gratuitamente ao artigo completo, clique em <strong><a href=\"https:\/\/www.insights.bio\/cell-and-gene-therapy-insights\/journal\/article\/3016\/Building-rings-with-spheres-a-cell-therapy-approach-to-incontinence\">aqui<\/a><\/strong>.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><!-- divi:paragraph --><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><!-- \/divi:paragraph -->[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"<p>The causes and impacts of faecal incontinence are being highlighted in the latest edition of the Journal of Cell and Gene Therapy Insights. Sphincter injury is a primary cause of faecal incontinence, and this article explores how innovative technologies such as cell therapy could change the treatment landscape for these underserved patients. Read an extract of the article here: Faecal incontinence is a prevalent condition, that remains vastly underreported. The condition impacts the patients\u2019 quality of life and has negative socio-economic and environmental impact on the society. Current patient management guidelines recommend a stepwise approach to treating faecal incontinence, from conservative treatment options, through minimally invasive surgical options, all the way to first- and second-line surgical options. Unfortunately, the conservative treatments remain ineffective, and, in many cases, the surgical options are either not desirable or not suitable. Regenerative medicine, and specifically, cell therapy, has the potential to offer a curative treatment that is less invasive, more effective and efficient. Cell therapy technologies, while still under development, can improve the current state-of-play in the realm of faecal incontinence at the clinical, patient, and socio-economic level. The aim of this article is twofold. Firstly, it is to raise awareness about the silent [&hellip;]<\/p>","protected":false},"author":4,"featured_media":31426,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<!-- wp:paragraph -->\n<p>The causes and impacts of faecal incontinence are being highlighted in the latest edition of the Journal of Cell and Gene Therapy Insights. Sphincter injury is a primary cause of faecal incontinence, and this article explores how innovative technologies such as cell therapy could change the treatment landscape for these underserved patients.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>Read an extract of the article here:<br><em>Faecal incontinence is a prevalent condition, that remains vastly underreported. The condition impacts the patients\u2019 quality of life and has negative socio-economic and environmental impact on the society. Current patient management guidelines recommend a stepwise approach to treating faecal incontinence, from conservative treatment options, through minimally invasive surgical options, all the way to first- and second-line surgical options. Unfortunately, the conservative treatments remain ineffective, and, in many cases, the surgical options are either not desirable or not suitable. Regenerative medicine, and specifically, cell therapy, has the potential to offer a curative treatment that is less invasive, more effective and efficient. Cell therapy technologies, while still under development, can improve the current state-of-play in the realm of faecal incontinence at the clinical, patient, and socio-economic level. The aim of this article is twofold. Firstly, it is to raise awareness about the silent affliction that faecal incontinence is and about the impact that it has on patients and society. Secondly, it is to position cell therapy, relative to the current treatment approaches, including, for example, sacral nerve stimulation and sphincteroplasty, as to emphasise its potential to provide a suitable treatment alternative.<\/em><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>To access the full article for free, click\u00a0<strong><a href=\"https:\/\/www.insights.bio\/cell-and-gene-therapy-insights\/journal\/article\/3016\/Building-rings-with-spheres-a-cell-therapy-approach-to-incontinence\">here<\/a><\/strong>.<\/p>\n<!-- \/wp:paragraph -->","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[47],"tags":[],"class_list":["post-31429","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-news"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/posts\/31429","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/comments?post=31429"}],"version-history":[{"count":7,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/posts\/31429\/revisions"}],"predecessor-version":[{"id":31438,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/posts\/31429\/revisions\/31438"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/media\/31426"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/media?parent=31429"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/categories?post=31429"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/tags?post=31429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}