{"id":30450,"date":"2020-12-16T16:08:01","date_gmt":"2020-12-16T16:08:01","guid":{"rendered":"https:\/\/amelie-project.eu\/?page_id=30450"},"modified":"2026-07-01T10:12:20","modified_gmt":"2026-07-01T10:12:20","slug":"a-nossa-investigacao","status":"publish","type":"page","link":"https:\/\/amelie-project.eu\/pt\/a-nossa-investigacao\/","title":{"rendered":"A nossa investiga\u00e7\u00e3o"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Hero section&#8221; _builder_version=&#8221;4.16&#8243; background_image=&#8221;https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/AMELIEHEADERBACKGOUND-01-scaled.jpg&#8221; background_position=&#8221;center_left&#8221; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;7%||7%||true|false&#8221; custom_padding_tablet=&#8221;15%||15%||true|false&#8221; custom_padding_phone=&#8221;&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; module_alignment=&#8221;left&#8221; custom_padding=&#8221;|||4%|false|false&#8221; custom_padding_tablet=&#8221;|||5%|false|false&#8221; custom_padding_phone=&#8221;|||5.5%|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][dsm_block_reveal_text block_reveal_text=&#8221;OUR RESEARCH&#8221; heading_html_tag=&#8221;h1&#8243; block_reveal_color=&#8221;#0e94f9&#8243; block_reveal_delay=&#8221;0&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;AMELIE||||||||&#8221; header_text_color=&#8221;#0e94f9&#8243; header_font_size=&#8221;3vw&#8221; custom_padding=&#8221;||||false|false&#8221; custom_padding_tablet=&#8221;||||false|false&#8221; custom_padding_phone=&#8221;||||false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; header_font_size_tablet=&#8221;5vw&#8221; header_font_size_phone=&#8221;6vw&#8221; header_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][\/dsm_block_reveal_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; admin_label=&#8221;Collections&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;100px|0px|100px|0px|false|false&#8221; custom_padding_tablet=&#8221;50px||50px||true|false&#8221; custom_padding_phone=&#8221;&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;2_5,3_5&#8243; make_equal=&#8221;on&#8221; custom_padding_last_edited=&#8221;off|tablet&#8221; module_id=&#8221;faecal-incontinence-about-the-condition&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|||&#8221; custom_margin_tablet=&#8221;||||false|false&#8221; custom_margin_phone=&#8221;&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;0px||0px|&#8221; box_shadow_style=&#8221;preset3&#8243; box_shadow_vertical=&#8221;40px&#8221; box_shadow_blur=&#8221;50px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.1)&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.16&#8243; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;35deg&#8221; background_color_gradient_stops=&#8221;#6bc8ff 0%|#99afff 100%&#8221; background_color_gradient_start=&#8221;#6bc8ff&#8221; background_color_gradient_end=&#8221;#99afff&#8221; background_image=&#8221;https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/12\/Asset-1.png&#8221; custom_padding=&#8221;5%|5%|5%|5%|true|false&#8221; custom_padding_tablet=&#8221;15%||15%||true|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; admin_label=&#8221;Column&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;40px|40px|40px|40px&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;AMELIE||||||||&#8221; header_font=&#8221;Gotham kinda bold||||||||&#8221; header_text_color=&#8221;#000000&#8243; header_3_font=&#8221;Gotham kinda bold||||||||&#8221; header_3_text_color=&#8221;#000000&#8243; header_3_font_size=&#8221;28px&#8221; header_3_line_height=&#8221;1.5em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_margin=&#8221;||10px|&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Incontin\u00eancia fecal: impacto nos doentes<\/h3>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;Gotham kinda bold||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;1.9em&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;||||||||&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span style=\"font-weight: 400;\">A incontin\u00eancia fecal constitui um problema de sa\u00fade p\u00fablica de grande relev\u00e2ncia. <\/span>Esta condi\u00e7\u00e3o pode afetar gravemente a vida quotidiana, nomeadamente:<\/p>\n<ul>\n<li>dignidade e confian\u00e7a<\/li>\n<li>bem-estar e sa\u00fade mental<\/li>\n<li>independ\u00eancia<\/li>\n<\/ul>\n<div class=\"x_elementToProof\">Muitas pessoas sentem:<\/div>\n<ul>\n<li>ansiedade<\/li>\n<li>isolamento social<\/li>\n<li>menor participa\u00e7\u00e3o no trabalho e nas desloca\u00e7\u00f5es<\/li>\n<li>limita\u00e7\u00f5es nas atividades di\u00e1rias<\/li>\n<\/ul>\n<div class=\"x_elementToProof\">O projeto AMELIE centra-se especificamente na incontin\u00eancia fecal resultante de les\u00f5es no esf\u00edncter anal, na maioria dos casos na sequ\u00eancia de:<\/div>\n<ul>\n<li>parto<\/li>\n<li>cirurgia<\/li>\n<li>trauma<\/li>\n<\/ul>\n<div class=\"x_elementToProof\">As mulheres que j\u00e1 deram \u00e0 luz representam uma grande propor\u00e7\u00e3o das pessoas afetadas, sendo que cerca de 5,5% sofrem les\u00f5es diretas durante o parto devido a lacera\u00e7\u00f5es perineais.<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|tablet&#8221; admin_label=&#8221;Collections&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;0px|0px|100px|0px|false|false&#8221; custom_padding_tablet=&#8221;||50px||false|false&#8221; custom_padding_phone=&#8221;&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;3_5,2_5&#8243; make_equal=&#8221;on&#8221; module_id=&#8221;faecal-incontinence-and-regenerative-medicine&#8221; _builder_version=&#8221;4.27.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;0px||0px|&#8221; hover_enabled=&#8221;0&#8243; box_shadow_style=&#8221;preset3&#8243; box_shadow_vertical=&#8221;40px&#8221; box_shadow_blur=&#8221;50px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.1)&#8221; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;][et_pb_column type=&#8221;3_5&#8243; admin_label=&#8221;Column&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;40px|40px|40px|40px&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221; custom_css_main_element_last_edited=&#8221;off|phone&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;AMELIE||||||||&#8221; header_font=&#8221;Gotham kinda bold||||||||&#8221; header_text_color=&#8221;#000000&#8243; header_3_font=&#8221;Gotham kinda bold||||||||&#8221; header_3_text_color=&#8221;#000000&#8243; header_3_font_size=&#8221;28px&#8221; header_3_line_height=&#8221;1.5em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_margin=&#8221;||10px|&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Incontin\u00eancia fecal e medicina regenerativa<\/h3>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;Gotham kinda bold||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;1.9em&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;||||||||&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"x_elementToProof\" data-olk-copy-source=\"MessageBody\">\n<p>A medicina regenerativa visa reparar ou substituir tecido danificado pelo envelhecimento, por doen\u00e7a ou por les\u00e3o, oferecendo novas possibilidades para o tratamento da incontin\u00eancia fecal causada por les\u00f5es no esf\u00edncter anal. Entre as abordagens regenerativas, a terapia celular que utiliza c\u00e9lulas aut\u00f3logas derivadas do m\u00fasculo esquel\u00e9tico (ASMDCs) para regenerar o esf\u00edncter anal externo danificado tem sido a mais amplamente investigada.<\/p>\n<\/div>\n<div class=\"x_elementToProof\" data-olk-copy-source=\"MessageBody\"><\/div>\n<div class=\"x_elementToProof\">A Europa tem desempenhado um papel de lideran\u00e7a na transposi\u00e7\u00e3o desta abordagem para a pr\u00e1tica cl\u00ednica. Dos cinco estudos cl\u00ednicos publicados sobre terapia celular para a incontin\u00eancia fecal, tr\u00eas foram realizados por grupos de investiga\u00e7\u00e3o europeus e utilizaram ASMDCs administradas sob a forma de suspens\u00e3o celular. No ensaio cl\u00ednico de Fase II, aleat\u00f3rio e controlado por placebo, apenas 58% dos doentes que receberam terapia com ASMDC apresentaram resposta ap\u00f3s 12 meses, enquanto estudos-piloto abertos relataram n\u00edveis semelhantes de melhoria subjetiva. Em geral, estes estudos demonstraram apenas um benef\u00edcio cl\u00ednico modesto, sugerindo que os atuais m\u00e9todos de administra\u00e7\u00e3o celular n\u00e3o alcan\u00e7am de forma consistente o efeito terap\u00eautico desejado.<\/div>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.16&#8243; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;35deg&#8221; background_color_gradient_stops=&#8221;#6bc8ff 0%|#99afff 100%&#8221; background_color_gradient_start=&#8221;#6bc8ff&#8221; background_color_gradient_end=&#8221;#99afff&#8221; background_image=&#8221;https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/12\/Asset-3.png&#8221; custom_padding=&#8221;5%|5%|5%|5%|true|false&#8221; custom_padding_tablet=&#8221;15%||15%||true|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221; custom_css_main_element_last_edited=&#8221;off|desktop&#8221;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|tablet&#8221; admin_label=&#8221;Collections&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;0px|0px|100px|0px|false|false&#8221; custom_padding_tablet=&#8221;||100px||false|false&#8221; custom_padding_phone=&#8221;&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;2_5,3_5&#8243; make_equal=&#8221;on&#8221; module_id=&#8221;why-are-conventional-methods-not-working&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;0px||0px|&#8221; box_shadow_style=&#8221;preset3&#8243; box_shadow_vertical=&#8221;40px&#8221; box_shadow_blur=&#8221;50px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.1)&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.16&#8243; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;35deg&#8221; background_color_gradient_stops=&#8221;#6bc8ff 0%|#99afff 100%&#8221; background_color_gradient_start=&#8221;#6bc8ff&#8221; background_color_gradient_end=&#8221;#99afff&#8221; background_image=&#8221;https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/12\/Asset-2.png&#8221; custom_padding=&#8221;5%|5%|5%|5%|true|false&#8221; custom_padding_tablet=&#8221;15%||15%||true|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; admin_label=&#8221;Column&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;40px|40px|40px|40px&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;AMELIE||||||||&#8221; header_font=&#8221;Gotham kinda bold||||||||&#8221; header_text_color=&#8221;#000000&#8243; header_3_font=&#8221;Gotham kinda bold||||||||&#8221; header_3_text_color=&#8221;#000000&#8243; header_3_font_size=&#8221;28px&#8221; header_3_line_height=&#8221;1.5em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_margin=&#8221;||10px|&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Por que raz\u00e3o os m\u00e9todos convencionais n\u00e3o est\u00e3o a produzir melhores resultados?<\/h3>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;Gotham kinda bold||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;1.9em&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;||||||||&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"x_elementToProof\" data-olk-copy-source=\"MessageBody\">Muitas das c\u00e9lulas utilizadas na medicina regenerativa, incluindo as c\u00e9lulas aut\u00f3logas derivadas do m\u00fasculo esquel\u00e9tico (ASMDCs), s\u00e3o<span>\u00a0<\/span><b>dependente de ancoragem<\/b>, o que significa que t\u00eam de permanecer fixadas a uma superf\u00edcie para crescerem e funcionarem normalmente. Na produ\u00e7\u00e3o convencional, estas c\u00e9lulas s\u00e3o isoladas do doente, multiplicadas em laborat\u00f3rio enquanto permanecem fixadas a uma superf\u00edcie de cultura e, posteriormente, desprendidas antes de serem administradas sob a forma de suspens\u00e3o celular.<\/div>\n<div class=\"x_elementToProof\">At\u00e9 \u00e0 data, todos os estudos cl\u00ednicos publicados sobre terapia celular para a incontin\u00eancia fecal utilizaram esta abordagem convencional de produ\u00e7\u00e3o. No entanto, a separa\u00e7\u00e3o das c\u00e9lulas da sua superf\u00edcie de cultura antes do transplante pode danific\u00e1-las, reduzindo a sua viabilidade e potencial regenerativo. Este processo tamb\u00e9m pode desencadear a anoikis \u2014 uma forma de morte celular que ocorre quando as c\u00e9lulas dependentes de ancoragem perdem o contacto com a superf\u00edcie de suporte.<\/div>\n<div class=\"x_elementToProof\">A baixa sobreviv\u00eancia celular ap\u00f3s o transplante \u00e9 um dos principais desafios com que se depara a medicina regenerativa. No caso das terapias que dependem da integra\u00e7\u00e3o das c\u00e9lulas no m\u00fasculo danificado, como os tratamentos para a incontin\u00eancia fecal, a baixa sobreviv\u00eancia celular pode limitar a efic\u00e1cia e contribuir para resultados cl\u00ednicos inconsistentes.<\/div>\n<div class=\"x_elementToProof\">Enfrentar este desafio est\u00e1 no cerne do projeto AMELIE. Atrav\u00e9s do desenvolvimento de uma terapia com c\u00e9lulas e microportadores implant\u00e1veis que permite que as c\u00e9lulas permane\u00e7am fixadas a uma estrutura de suporte durante o transplante, o cons\u00f3rcio pretende melhorar a sobreviv\u00eancia celular, potenciar a repara\u00e7\u00e3o dos tecidos e proporcionar melhores resultados aos doentes.<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px|||||&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"<p><div class=\"et_pb_module dsm_block_reveal_text dsm_block_reveal_text_0\">\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t<div class=\"et_pb_module_inner\">\n\t\t\t\t\t<div class=\"dsm_block_reveal_text_wrapper\" data-dsm-block-reveal-animation=\"lr\" data-dsm-block-reveal-color=\"#0e94f9\" data-dsm-block-reveal-delay=\"0\" data-dsm-block-reveal-viewport=\"80%\"><h1 class=\"dsm_block_reveal_text_header et_pb_module_header\">A NOSSA INVESTIGA\u00c7\u00c3O<\/h1><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Faecal Incontinence: Impact on PatientsFaecal incontinence is a substantial public health problem. The condition can severely affect everyday life, including: dignity and confidence wellbeing and mental health independence Many individuals experience: anxiety social isolation reduced participation in work and travel limitations in daily activities The AMELIE project focuses specifically on faecal incontinence resulting from injury to the anal sphincter, most commonly following: childbirth surgery trauma Women who have given birth represent a large proportion of affected individuals, with around 5.5% experiencing direct injury during childbirth due to perineal tearing.Faecal Incontinence and Regenerative Medicine Regenerative medicine seeks to repair or replace tissue that has been damaged by ageing, disease or injury, offering new possibilities for treating faecal incontinence caused by injury to the anal sphincter. Among regenerative approaches, cell therapy using autologous skeletal muscle-derived cells (ASMDCs) to regenerate the damaged external anal sphincter has been the most extensively investigated. Europe has played a leading role in translating this approach into clinical practice. Of the five published clinical studies of cell therapy for faecal incontinence, three were conducted by European research groups and used [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-30450","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/30450","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/comments?post=30450"}],"version-history":[{"count":23,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/30450\/revisions"}],"predecessor-version":[{"id":31786,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/30450\/revisions\/31786"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/media?parent=30450"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}