{"id":28691,"date":"2020-09-05T00:19:04","date_gmt":"2020-09-05T00:19:04","guid":{"rendered":"https:\/\/amelie-project.eu\/?page_id=28691"},"modified":"2026-07-01T10:07:51","modified_gmt":"2026-07-01T10:07:51","slug":"visao-e-objectivos","status":"publish","type":"page","link":"https:\/\/amelie-project.eu\/pt\/visao-e-objectivos\/","title":{"rendered":"Vis\u00e3o e objectivos"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”Hero section” _builder_version=”4.16″ _module_preset=”ac17d3a6-8373-45ed-95ce-70484e82a9b6″ use_background_color_gradient=”off” saved_tabs=”all” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.16″ _module_preset=”default” width=”100%” module_alignment=”left” custom_padding=”|||4%|false|false” custom_padding_tablet=”|||6%|false|false” custom_padding_phone=”|||7%|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][dsm_block_reveal_text block_reveal_text=”VISION” heading_html_tag=”h1″ block_reveal_color=”#0e94f9″ block_reveal_delay=”0″ _builder_version=”4.16″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”4vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”8vw” header_font_size_phone=”10vw” header_font_size_last_edited=”on|desktop” global_colors_info=”{}”][\/dsm_block_reveal_text][dsm_block_reveal_text block_reveal_text=”AND OBJECTIVES” block_reveal_color=”#0e94f9″ _builder_version=”4.16″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”3vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”5vw” header_font_size_phone=”6vw” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/dsm_block_reveal_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Features” _builder_version=”4.16″ background_enable_color=”off” custom_padding=”100px|0px|100px|0px||” global_colors_info=”{}”][et_pb_row column_structure=”1_3,1_3,1_3″ admin_label=”Sending Payments” _builder_version=”4.16″ max_width=”1440px” custom_margin=”|||” use_custom_width=”on” custom_width_px=”1440px” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/shutterstock_1069097789-Converted-1.png” title_text=”shutterstock_1069097789 %91Converted%93″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”10%” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.16″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.8em” header_font=”||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_color=”#000000″ header_2_font_size=”32px” header_2_line_height=”1.3em” header_3_font=”||||||||” header_4_font=”||||||||” text_orientation=”center” global_colors_info=”{}”]<\/p>\n

A nossa miss\u00e3o<\/h2>\n

O cons\u00f3rcio est\u00e1 a ser pioneiro numa nova abordagem translacional para o fabrico e a administra\u00e7\u00e3o de c\u00e9lulas dependentes de ancoragem. Ao permitir que as c\u00e9lulas sejam implantadas mantendo-se fixadas a uma estrutura de suporte, esta tecnologia tem o potencial de melhorar as terapias de medicina regenerativa para a incontin\u00eancia fecal e muitas outras aplica\u00e7\u00f5es cl\u00ednicas.<\/span><\/p>\n

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A Necessidade N\u00e3o Satisfazida<\/h2>\n
A incontin\u00eancia fecal afeta mais de 67 milh\u00f5es de pessoas em toda a Europa, representando um desafio de sa\u00fade p\u00fablica comum, mas pouco reconhecido.<\/div>\n
Embora n\u00e3o seja fatal, \u00e9 classificada pela Organiza\u00e7\u00e3o Mundial de Sa\u00fade (OMS) como uma doen\u00e7a que pode ter um impacto profundo na qualidade de vida, <\/span>funcionamento di\u00e1rio, <\/span>produtividade, e <\/span>sistemas de sa\u00fade.<\/span><\/div>\n
Apesar da sua preval\u00eancia, as op\u00e7\u00f5es de tratamento atuais continuam a ser limitadas. Muitas vezes, s\u00e3o invasivas, n\u00e3o s\u00e3o adequadas para todos os doentes ou n\u00e3o proporcionam benef\u00edcios duradouros a longo prazo, o que cria uma necessidade cl\u00ednica n\u00e3o satisfeita significativa.<\/div>\n

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A nossa vis\u00e3o<\/h2>\n

A AMELIE est\u00e1 a desenvolver um produto inovador de engenharia de tecidos, classificado como um medicamento de terapia avan\u00e7ada combinada, no qual c\u00e9lulas dependentes de ancoragem s\u00e3o fixadas a um microportador implant\u00e1vel, biodegrad\u00e1vel e clinicamente qualificado, com o objetivo de melhorar diretamente os sintomas cl\u00ednicos da incontin\u00eancia fecal.<\/span><\/p>\n

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AMELIE Objectivos<\/h2>\n

[\/et_pb_text][et_pb_blurb title=”Objective 1:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1093px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Estabelecer novos processos robustos para o fabrico, carateriza\u00e7\u00e3o, transporte e entrega de microtransportadores biodegrad\u00e1veis e implant\u00e1veis<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 2:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Demonstrar a seguran\u00e7a dos microtransportadores ASMDC utilizando testes n\u00e3o cl\u00ednicos para cumprir os requisitos regulamentares nacionais e criar um resumo do produto que permita a avalia\u00e7\u00e3o da tecnologia em toda a Europa.<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 3:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1127px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Realizar um ensaio pan-europeu aleat\u00f3rio e em dupla oculta\u00e7\u00e3o para determinar se os microtransportadores conduzem a uma redu\u00e7\u00e3o da frequ\u00eancia dos epis\u00f3dios de FI.<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 4:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Envolver as sociedades nacionais e regionais com o apoio das institui\u00e7\u00f5es de caridade europeias, das redes de apoio aos doentes e do p\u00fablico para estabelecer canais para a atividade da IPP e a divulga\u00e7\u00e3o dos desenvolvimentos do projeto aos doentes, ao p\u00fablico e \u00e0 comunidade cient\u00edfica.<\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 5:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1051px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|25px|40px|false|false” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Desenvolver um plano de neg\u00f3cios e uma futura estrat\u00e9gia de comercializa\u00e7\u00e3o para permitir o acesso dos doentes ao microcarrier em toda a Europa e no mundo.<\/span><\/p>\n

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VIS\u00c3O<\/h1><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
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E OBJECTIVOS<\/h2><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Our Mission The consortium is pioneering a novel translational approach to the manufacture and delivery of anchorage-dependent cells. By enabling cells to be implanted while remaining attached to a supportive scaffold, this technology has the potential to improve regenerative medicine therapies for faecal incontinence and many other clinical applications.The Unmet Need Faecal incontinence affects more than 67 million people across Europe, representing a common but under-recognised public health challenge. Although not life-threatening, it is classified by the World Health Organisation (WHO) as a disease that can have a profound impact on quality of life, daily functioning, productivity, and healthcare systems. Despite its prevalence, current treatment options remain limited. They are often invasive, not suitable for all patients, or fail to provide durable long-term benefit, creating a significant unmet clinical need.Our Vision AMELIE is developing a novel tissue-engineered product, classified as a combined advanced therapy medicinal product, in which anchorage-dependent cells are attached to an implantable, biodegradable and clinically qualified microcarrier with the aim of directly improving the […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-28691","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/28691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/comments?post=28691"}],"version-history":[{"count":42,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/28691\/revisions"}],"predecessor-version":[{"id":31779,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/28691\/revisions\/31779"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/media?parent=28691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}