{"id":28371,"date":"2020-09-03T09:02:33","date_gmt":"2020-09-03T09:02:33","guid":{"rendered":"https:\/\/amelie-project.eu\/?page_id=28371"},"modified":"2021-01-26T10:47:43","modified_gmt":"2021-01-26T10:47:43","slug":"beneficios-de-amelie","status":"publish","type":"page","link":"https:\/\/amelie-project.eu\/pt\/beneficios-de-amelie\/","title":{"rendered":"Benef\u00edcios da AMELIE"},"content":{"rendered":"[et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” disabled_on=”off|off|off” admin_label=”Hero section” _builder_version=”4.6.3″ background_image=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/AMELIEHEADERBACKGOUND-01-scaled.jpg” background_position=”center_left” custom_margin=”|||” custom_padding=”7%||7%||true|false” custom_padding_tablet=”15%||15%||true|false” custom_padding_phone=””][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.6.3″ _module_preset=”default” width=”100%” module_alignment=”left” custom_padding=”|||4%|false|false” custom_padding_tablet=”|||6%|false|false” custom_padding_phone=”|||7%|false|false”][et_pb_column type=”4_4″ _builder_version=”4.6.3″ _module_preset=”default”][dsm_block_reveal_text block_reveal_text=”BENEFITS” heading_html_tag=”h1″ block_reveal_color=”#0e94f9″ block_reveal_delay=”0″ _builder_version=”4.6.3″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”4vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”8vw” header_font_size_phone=”10vw” header_font_size_last_edited=”on|desktop”][\/dsm_block_reveal_text][dsm_block_reveal_text block_reveal_text=”OF AMELIE” block_reveal_color=”#0e94f9″ _builder_version=”4.6.3″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”3vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”6vw” header_font_size_phone=”7vw” header_font_size_last_edited=”on|desktop”][\/dsm_block_reveal_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.6.3″ transform_scale_tablet=”90%|90%” transform_scale_last_edited=”off|desktop” transform_translate_last_edited=”off|desktop” transform_rotate_last_edited=”off|desktop” transform_skew_last_edited=”off|desktop” transform_origin_last_edited=”off|desktop” transform_styles_last_edited=”off|desktop” custom_margin=”||||false|false” custom_padding=”100px|0px|100px|0px” custom_padding_tablet=”35px|0px|35px|0px|true|false” custom_padding_phone=”15px||15px||true|false”][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.6.3″ _module_preset=”default” animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”11%”][et_pb_column type=”1_3″ _builder_version=”4.6.3″ _module_preset=”default”][dsm_tilt_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/09\/science1shadow-4.png” title_text=”science1shadow” dsm_tilt_mobile=”on” dsm_tilt_scale=”1.1″ dsm_tilt_max=”15″ dsm_use_glare=”on” dsm_tilt_glare=”0.5″ _builder_version=”4.6.3″ _module_preset=”default”][\/dsm_tilt_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.6em” header_font=”Gotham kinda bold|||on|||||” header_text_color=”#000000″ header_font_size=”15px” header_letter_spacing=”1px” header_line_height=”1.4em” header_2_font=”Gotham kinda bold|||on|||||” header_2_text_color=”#000000″ header_2_font_size=”15px” header_2_letter_spacing=”1px” header_2_line_height=”1.4em” header_3_font=”Gotham kinda bold|||on|||||” header_3_text_color=”#000000″ header_3_font_size=”15px” header_3_letter_spacing=”1px” header_3_line_height=”1.4em” header_4_font=”Gotham kinda bold|||on|||||” header_4_text_color=”#000000″ header_4_font_size=”17px” header_4_letter_spacing=”1px” header_4_line_height=”1.4em” header_5_font=”Gotham kinda bold|||on|||||” header_5_text_color=”#000000″ header_5_font_size=”15px” header_5_letter_spacing=”1px” header_5_line_height=”1.4em” header_6_font=”Gotham kinda bold|||on|||||” header_6_text_color=”#000000″ header_6_font_size=”15px” header_6_letter_spacing=”1px” header_6_line_height=”1.4em” text_orientation=”center” max_width=”800px” module_alignment=”center” locked=”off”]

Identifica\u00e7\u00e3o de potenciais novas terapias regenerativas para responder a necessidades cl\u00ednicas n\u00e3o satisfeitas de grandes grupos de doentes.<\/p>[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.6.3″ _module_preset=”default”][dsm_tilt_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/09\/science2shadow.png” title_text=”science2shadow” dsm_tilt_mobile=”on” dsm_tilt_scale=”1.1″ dsm_tilt_max=”15″ dsm_use_glare=”on” dsm_tilt_glare=”0.5″ _builder_version=”4.6.3″ _module_preset=”default”][\/dsm_tilt_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.6em” header_font=”Gotham kinda bold|||on|||||” header_text_color=”#000000″ header_font_size=”15px” header_letter_spacing=”1px” header_line_height=”1.4em” header_2_font=”Gotham kinda bold|||on|||||” header_2_text_color=”#000000″ header_2_font_size=”15px” header_2_letter_spacing=”1px” header_2_line_height=”1.4em” header_3_font=”Gotham kinda bold|||on|||||” header_3_text_color=”#000000″ header_3_font_size=”15px” header_3_letter_spacing=”1px” header_3_line_height=”1.4em” header_4_font=”Gotham kinda bold|||on|||||” header_4_text_color=”#000000″ header_4_font_size=”17px” header_4_letter_spacing=”1px” header_4_line_height=”1.4em” header_5_font=”Gotham kinda bold|||on|||||” header_5_text_color=”#000000″ header_5_font_size=”15px” header_5_letter_spacing=”1px” header_5_line_height=”1.4em” header_6_font=”Gotham kinda bold|||on|||||” header_6_text_color=”#000000″ header_6_font_size=”15px” header_6_letter_spacing=”1px” header_6_line_height=”1.4em” text_orientation=”center” max_width=”800px” module_alignment=”center” locked=”off”]

A posi\u00e7\u00e3o da Europa no dom\u00ednio da medicina regenerativa translacional foi refor\u00e7ada.<\/p>[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.6.3″ _module_preset=”default”][dsm_tilt_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/09\/science3shadow-2.png” title_text=”science3shadow” dsm_tilt_mobile=”on” dsm_tilt_scale=”1.1″ dsm_tilt_max=”15″ dsm_use_glare=”on” dsm_tilt_glare=”0.5″ _builder_version=”4.6.3″ _module_preset=”default”][\/dsm_tilt_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.6em” header_font=”Gotham kinda bold|||on|||||” header_text_color=”#000000″ header_font_size=”15px” header_letter_spacing=”1px” header_line_height=”1.4em” header_2_font=”Gotham kinda bold|||on|||||” header_2_text_color=”#000000″ header_2_font_size=”15px” header_2_letter_spacing=”1px” header_2_line_height=”1.4em” header_3_font=”Gotham kinda bold|||on|||||” header_3_text_color=”#000000″ header_3_font_size=”15px” header_3_letter_spacing=”1px” header_3_line_height=”1.4em” header_4_font=”Gotham kinda bold|||on|||||” header_4_text_color=”#000000″ header_4_font_size=”17px” header_4_letter_spacing=”1px” header_4_line_height=”1.4em” header_5_font=”Gotham kinda bold|||on|||||” header_5_text_color=”#000000″ header_5_font_size=”15px” header_5_letter_spacing=”1px” header_5_line_height=”1.4em” header_6_font=”Gotham kinda bold|||on|||||” header_6_text_color=”#000000″ header_6_font_size=”15px” header_6_letter_spacing=”1px” header_6_line_height=”1.4em” text_orientation=”center” max_width=”800px” module_alignment=”center” locked=”off”]

Novas terapias para as principais doen\u00e7as e afec\u00e7\u00f5es humanas e novas abordagens terap\u00eauticas mais avan\u00e7adas na linha de desenvolvimento.<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ background_color=”rgba(0,0,0,0.03)” background_position=”top_center” custom_margin=”|||” custom_padding=”100px||100px|”][et_pb_row use_custom_gutter=”on” gutter_width=”4″ _builder_version=”4.6.3″ custom_margin=”||||false|false” custom_padding=”0px|||”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” parallax__hover=”off” parallax_method__hover=”on” custom_padding__hover=”|||”][et_pb_blurb title=”Potential new regenerative therapies to address unmet clinical needs of large patient groups identified” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” custom_margin=”|||” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(10,3,3,0.06)” locked=”off”]

A IF \u00e9 uma doen\u00e7a comum que afecta ~9% de adultos europeus. Este n\u00famero est\u00e1 subestimado, uma vez que ~70% dos doentes com IF n\u00e3o consultam um prestador de cuidados de sa\u00fade sobre a sua doen\u00e7a. Apenas uma parte dos que o fazem procurar\u00e1 tratamento adicional, mas ~50% n\u00e3o se adequar\u00e3o \u00e0s op\u00e7\u00f5es actuais. A abordagem da AMELIE tem numerosas vantagens em rela\u00e7\u00e3o a outras interven\u00e7\u00f5es cir\u00fargicas, que implicam o risco de infe\u00e7\u00e3o, dor e defeito\/luxa\u00e7\u00e3o do eletrodo, o que pode resultar num estoma permanente. O efeito da melhoria da contin\u00eancia ap\u00f3s o tratamento ter\u00e1 impacto para al\u00e9m das pessoas que sofrem imediatamente da doen\u00e7a, como os prestadores de cuidados e as pessoas em listas de espera de lares de idosos.<\/span>\u00a0<\/span><\/p>\n

Se for eficaz, o tratamento com a tecnologia de microtransportadores celulares implant\u00e1veis ter\u00e1 um impacto significativo na qualidade de vida dos cidad\u00e3os da UE.<\/span> Promo\u00e7\u00e3o deste tratamento como uma abordagem realista para <\/span>tratamento<\/span><\/i> A utiliza\u00e7\u00e3o de um tratamento para a incontin\u00eancia em vez da gest\u00e3o dos sintomas, aumentar\u00e1 a probabilidade de os doentes com IF consultarem um prestador de cuidados de sa\u00fade sobre a sua condi\u00e7\u00e3o e, assim, aumentar\u00e1 o n\u00famero de doentes a que o tratamento pode chegar.<\/span><\/p>[\/et_pb_blurb][et_pb_blurb title=”Europe\u2019s position in translational regenerative medicine strengthened ” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” custom_margin=”|||” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(10,3,3,0.06)” locked=”off” sticky_enabled=”0″]

A Europa \u00e9 l\u00edder mundial em terapias baseadas em c\u00e9lulas para doentes com IF.<\/span> Para al\u00e9m de refor\u00e7ar o papel dominante da Europa neste dom\u00ednio, a AMELIE representa tamb\u00e9m uma mudan\u00e7a radical na abordagem adoptada para fabricar e fornecer medicamentos baseados em c\u00e9lulas que permitir\u00e3o aos cidad\u00e3os europeus serem os primeiros a n\u00edvel mundial a beneficiar de uma nova abordagem pioneira da medicina regenerativa.\u00a0<\/span><\/p>\n

A terapia celular \u00e9 uma \u00e1rea de investiga\u00e7\u00e3o em r\u00e1pido crescimento. Os produtos de engenharia de tecidos dever\u00e3o registar um crescimento significativo e proporcionar oportunidades substanciais para refor\u00e7ar a posi\u00e7\u00e3o da Europa na medicina regenerativa translacional. A Europa \u00e9 respons\u00e1vel por cerca de 26% das empresas mundiais de medicina regenerativa. O desenvolvimento de tecnologias inovadoras, como os microcarregadores implant\u00e1veis TIPS, atrair\u00e1 investimentos para a Europa. A AMELIE procura ent\u00e3o promover as posi\u00e7\u00f5es competitivas das empresas europeias enquanto fornecedoras de tecnologias facilitadoras inovadoras para a medicina regenerativa. Isto refor\u00e7ar\u00e1 o potencial de explora\u00e7\u00e3o da AMELIE.<\/span><\/p>\n[\/et_pb_blurb][et_pb_blurb title=”New therapies for major human diseases and conditions, and new approaches for therapy taken further in the development pipeline” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” custom_margin=”|||” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(10,3,3,0.06)” locked=”off”]

A AMELIE abre caminho a tratamentos inovadores id\u00eanticos ou semelhantes utilizando combina\u00e7\u00f5es de c\u00e9lulas-microtransportadoras ASMDC para uma variedade de outras condi\u00e7\u00f5es cl\u00ednicas associadas \u00e0 perda de fun\u00e7\u00e3o do m\u00fasculo esquel\u00e9tico, como a incontin\u00eancia urin\u00e1ria, as distrofias musculares e a perda volum\u00e9trica do m\u00fasculo associada a les\u00f5es traum\u00e1ticas.\u00a0<\/span><\/p>\n

O mesmo racioc\u00ednio cient\u00edfico e a nova abordagem desenvolvida no AMELIE s\u00e3o igualmente aplic\u00e1veis a outros tipos de c\u00e9lulas dependentes de ancoragem investigados como novos tratamentos de medicina regenerativa. Os novos produtos compostos por estas c\u00e9lulas dependentes de ancoragem destinam-se a tratar algumas das doen\u00e7as mais debilitantes que afectam os tecidos muscular, \u00f3sseo, cartilaginoso, ocular, card\u00edaco\/cardiovascular, gastrointestinal\/f\u00edgado, renal, imunit\u00e1rio e respirat\u00f3rio. A ado\u00e7\u00e3o da tecnologia de microcarreadores TIPS implant\u00e1veis poder\u00e1 ter um impacto significativo nos seus resultados.<\/span><\/p>\n

Entretanto, o processo de fabrico em escala para micropart\u00edculas TIPS desenvolvido pode ser aplicado a outras utiliza\u00e7\u00f5es da tecnologia de micropart\u00edculas que est\u00e3o atualmente a ser investigadas na linha de desenvolvimento. <\/span><\/p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.6.3″ _module_preset=”default”][\/et_pb_section]","protected":false},"excerpt":{"rendered":"

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BENEF\u00cdCIOS<\/h1><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
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DE AMELIE<\/h2><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t
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\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\"\"<\/span>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Identifica\u00e7\u00e3o de potenciais novas terapias regenerativas para responder a necessidades cl\u00ednicas n\u00e3o satisfeitas de grandes grupos de doentes.
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t
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\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\"\"<\/span>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>A posi\u00e7\u00e3o da Europa no dom\u00ednio da medicina regenerativa translacional foi refor\u00e7ada.
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t
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\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\"\"<\/span>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>New therapies for major human diseases and conditions, and new approaches for therapy taken further in the development pipeline.FI is a common condition affecting ~9% European adults. This figure is underestimated as ~70% of patients with FI do not consult a healthcare provider about their condition. Only a proportion of those that do will seek further treatment, but ~50% will not be suited to current options. AMELIE\u2019s approach has numerous advantages over other surgical interventions, which risk infection, pain and lead defect\/dislocation, which can result in permanent stoma. The effect of improved continence following treatment will have impact beyond those immediately suffering the condition, such as carers and those on nursing home waiting lists.\u00a0 If effective, treatment with the implantable cell-microcarrier technology will […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-28371","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/28371","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/comments?post=28371"}],"version-history":[{"count":53,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/28371\/revisions"}],"predecessor-version":[{"id":31152,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/28371\/revisions\/31152"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/media?parent=28371"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}