{"id":28371,"date":"2020-09-03T09:02:33","date_gmt":"2020-09-03T09:02:33","guid":{"rendered":"https:\/\/amelie-project.eu\/?page_id=28371"},"modified":"2026-07-01T10:15:54","modified_gmt":"2026-07-01T10:15:54","slug":"beneficios-de-amelie","status":"publish","type":"page","link":"https:\/\/amelie-project.eu\/pt\/beneficios-de-amelie\/","title":{"rendered":"Benef\u00edcios da AMELIE"},"content":{"rendered":"

[et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” disabled_on=”off|off|off” admin_label=”Hero section” _builder_version=”4.16″ background_image=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/AMELIEHEADERBACKGOUND-01-scaled.jpg” background_position=”center_left” custom_margin=”|||” custom_padding=”7%||7%||true|false” custom_padding_tablet=”15%||15%||true|false” custom_padding_phone=”” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.16″ _module_preset=”default” width=”100%” module_alignment=”left” custom_padding=”|||4%|false|false” custom_padding_tablet=”|||6%|false|false” custom_padding_phone=”|||7%|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][dsm_block_reveal_text block_reveal_text=”BENEFITS” heading_html_tag=”h1″ block_reveal_color=”#0e94f9″ block_reveal_delay=”0″ _builder_version=”4.16″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”4vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”8vw” header_font_size_phone=”10vw” header_font_size_last_edited=”on|desktop” global_colors_info=”{}”][\/dsm_block_reveal_text][dsm_block_reveal_text block_reveal_text=”OF AMELIE” block_reveal_color=”#0e94f9″ _builder_version=”4.16″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”3vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”6vw” header_font_size_phone=”7vw” header_font_size_last_edited=”on|desktop” global_colors_info=”{}”][\/dsm_block_reveal_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.16″ transform_scale_tablet=”90%|90%” transform_scale_last_edited=”off|desktop” transform_translate_last_edited=”off|desktop” transform_rotate_last_edited=”off|desktop” transform_skew_last_edited=”off|desktop” transform_origin_last_edited=”off|desktop” transform_styles_last_edited=”off|desktop” custom_margin=”||||false|false” custom_padding=”100px|0px|100px|0px” custom_padding_tablet=”35px|0px|35px|0px|true|false” custom_padding_phone=”15px||15px||true|false” global_colors_info=”{}”][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.16″ _module_preset=”default” animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”11%” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][dsm_tilt_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/09\/science1shadow-4.png” title_text=”science1shadow” dsm_tilt_mobile=”on” dsm_tilt_scale=”1.1″ dsm_tilt_max=”15″ dsm_use_glare=”on” dsm_tilt_glare=”0.5″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/dsm_tilt_image][et_pb_text _builder_version=”4.16″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.6em” header_font=”Gotham kinda bold|||on|||||” header_text_color=”#000000″ header_font_size=”15px” header_letter_spacing=”1px” header_line_height=”1.4em” header_2_font=”Gotham kinda bold|||on|||||” header_2_text_color=”#000000″ header_2_font_size=”15px” header_2_letter_spacing=”1px” header_2_line_height=”1.4em” header_3_font=”Gotham kinda bold|||on|||||” header_3_text_color=”#000000″ header_3_font_size=”15px” header_3_letter_spacing=”1px” header_3_line_height=”1.4em” header_4_font=”Gotham kinda bold|||on|||||” header_4_text_color=”#000000″ header_4_font_size=”17px” header_4_letter_spacing=”1px” header_4_line_height=”1.4em” header_5_font=”Gotham kinda bold|||on|||||” header_5_text_color=”#000000″ header_5_font_size=”15px” header_5_letter_spacing=”1px” header_5_line_height=”1.4em” header_6_font=”Gotham kinda bold|||on|||||” header_6_text_color=”#000000″ header_6_font_size=”15px” header_6_letter_spacing=”1px” header_6_line_height=”1.4em” text_orientation=”center” max_width=”800px” module_alignment=”center” locked=”off” global_colors_info=”{}”]<\/p>\n

Identifica\u00e7\u00e3o de potenciais novas terapias regenerativas para responder a necessidades cl\u00ednicas n\u00e3o satisfeitas de grandes grupos de doentes.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][dsm_tilt_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/09\/science2shadow.png” title_text=”science2shadow” dsm_tilt_mobile=”on” dsm_tilt_scale=”1.1″ dsm_tilt_max=”15″ dsm_use_glare=”on” dsm_tilt_glare=”0.5″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/dsm_tilt_image][et_pb_text _builder_version=”4.16″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.6em” header_font=”Gotham kinda bold|||on|||||” header_text_color=”#000000″ header_font_size=”15px” header_letter_spacing=”1px” header_line_height=”1.4em” header_2_font=”Gotham kinda bold|||on|||||” header_2_text_color=”#000000″ header_2_font_size=”15px” header_2_letter_spacing=”1px” header_2_line_height=”1.4em” header_3_font=”Gotham kinda bold|||on|||||” header_3_text_color=”#000000″ header_3_font_size=”15px” header_3_letter_spacing=”1px” header_3_line_height=”1.4em” header_4_font=”Gotham kinda bold|||on|||||” header_4_text_color=”#000000″ header_4_font_size=”17px” header_4_letter_spacing=”1px” header_4_line_height=”1.4em” header_5_font=”Gotham kinda bold|||on|||||” header_5_text_color=”#000000″ header_5_font_size=”15px” header_5_letter_spacing=”1px” header_5_line_height=”1.4em” header_6_font=”Gotham kinda bold|||on|||||” header_6_text_color=”#000000″ header_6_font_size=”15px” header_6_letter_spacing=”1px” header_6_line_height=”1.4em” text_orientation=”center” max_width=”800px” module_alignment=”center” locked=”off” global_colors_info=”{}”]<\/p>\n

A posi\u00e7\u00e3o da Europa no dom\u00ednio da medicina regenerativa translacional foi refor\u00e7ada.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][dsm_tilt_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/09\/science3shadow-2.png” title_text=”science3shadow” dsm_tilt_mobile=”on” dsm_tilt_scale=”1.1″ dsm_tilt_max=”15″ dsm_use_glare=”on” dsm_tilt_glare=”0.5″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/dsm_tilt_image][et_pb_text _builder_version=”4.16″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.6em” header_font=”Gotham kinda bold|||on|||||” header_text_color=”#000000″ header_font_size=”15px” header_letter_spacing=”1px” header_line_height=”1.4em” header_2_font=”Gotham kinda bold|||on|||||” header_2_text_color=”#000000″ header_2_font_size=”15px” header_2_letter_spacing=”1px” header_2_line_height=”1.4em” header_3_font=”Gotham kinda bold|||on|||||” header_3_text_color=”#000000″ header_3_font_size=”15px” header_3_letter_spacing=”1px” header_3_line_height=”1.4em” header_4_font=”Gotham kinda bold|||on|||||” header_4_text_color=”#000000″ header_4_font_size=”17px” header_4_letter_spacing=”1px” header_4_line_height=”1.4em” header_5_font=”Gotham kinda bold|||on|||||” header_5_text_color=”#000000″ header_5_font_size=”15px” header_5_letter_spacing=”1px” header_5_line_height=”1.4em” header_6_font=”Gotham kinda bold|||on|||||” header_6_text_color=”#000000″ header_6_font_size=”15px” header_6_letter_spacing=”1px” header_6_line_height=”1.4em” text_orientation=”center” max_width=”800px” module_alignment=”center” locked=”off” global_colors_info=”{}”]<\/p>\n

Novas terapias para as principais doen\u00e7as e afec\u00e7\u00f5es humanas e novas abordagens terap\u00eauticas mais avan\u00e7adas na linha de desenvolvimento.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ background_color=”rgba(0,0,0,0.03)” background_position=”top_center” custom_margin=”|||” custom_padding=”100px||100px|” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” gutter_width=”4″ _builder_version=”4.16″ custom_margin=”||||false|false” custom_padding=”0px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” parallax__hover=”off” parallax_method__hover=”on” custom_padding__hover=”|||”][et_pb_blurb title=”Potential new regenerative therapies to address unmet clinical needs of large patient groups identified” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” custom_margin=”|||” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(10,3,3,0.06)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

A incontin\u00eancia fecal \u00e9 uma condi\u00e7\u00e3o comum que afeta aproximadamente 9% de adultos na Europa. No entanto, este n\u00famero est\u00e1 provavelmente subestimado, uma vez que cerca de 70% de indiv\u00edduos n\u00e3o procuram aconselhamento m\u00e9dico. Entre aqueles que consultam um profissional de sa\u00fade, apenas uma parte prossegue com o tratamento, e cerca de metade n\u00e3o \u00e9 eleg\u00edvel para as op\u00e7\u00f5es atualmente dispon\u00edveis.<\/div>\n
A abordagem AMELIE oferece v\u00e1rias vantagens em rela\u00e7\u00e3o \u00e0s interven\u00e7\u00f5es cir\u00fargicas existentes, que podem acarretar riscos como infe\u00e7\u00e3o, dor e falha ou deslocamento do dispositivo, levando, por vezes, \u00e0 necessidade de um estoma permanente. A melhoria dos resultados em termos de contin\u00eancia tem o potencial de beneficiar n\u00e3o s\u00f3 os doentes, mas tamb\u00e9m os cuidadores e as pessoas em listas de espera para lares de idosos.<\/div>\n
Se for eficaz, o tratamento que recorre \u00e0 tecnologia de microportadores celulares implant\u00e1veis poder\u00e1 melhorar significativamente a qualidade de vida dos cidad\u00e3os em toda a Europa. Apresentar esta terapia como uma op\u00e7\u00e3o realista para restaurar a contin\u00eancia, em vez de se limitar apenas ao controlo dos sintomas, poder\u00e1 tamb\u00e9m incentivar mais doentes a procurar aconselhamento m\u00e9dico, aumentando assim o acesso ao tratamento.<\/div>\n

[\/et_pb_blurb][et_pb_blurb title=”Europe\u2019s position in translational regenerative medicine strengthened ” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” custom_margin=”|||” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(10,3,3,0.06)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

A Europa \u00e9 l\u00edder mundial em terapias baseadas em c\u00e9lulas para doentes com IF.<\/span> Para al\u00e9m de refor\u00e7ar o papel dominante da Europa neste dom\u00ednio, a AMELIE representa tamb\u00e9m uma mudan\u00e7a radical na abordagem adoptada para fabricar e fornecer medicamentos baseados em c\u00e9lulas que permitir\u00e3o aos cidad\u00e3os europeus serem os primeiros a n\u00edvel mundial a beneficiar de uma nova abordagem pioneira da medicina regenerativa.\u00a0<\/span><\/p>\n

A terapia celular \u00e9 uma \u00e1rea de investiga\u00e7\u00e3o em r\u00e1pido crescimento. Os produtos de engenharia de tecidos dever\u00e3o registar um crescimento significativo e proporcionar oportunidades substanciais para refor\u00e7ar a posi\u00e7\u00e3o da Europa na medicina regenerativa translacional. A Europa \u00e9 respons\u00e1vel por cerca de 26% das empresas mundiais de medicina regenerativa. O desenvolvimento de tecnologias inovadoras, como os microcarregadores implant\u00e1veis TIPS, atrair\u00e1 investimentos para a Europa. A AMELIE procura ent\u00e3o promover as posi\u00e7\u00f5es competitivas das empresas europeias enquanto fornecedoras de tecnologias facilitadoras inovadoras para a medicina regenerativa. Isto refor\u00e7ar\u00e1 o potencial de explora\u00e7\u00e3o da AMELIE.<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”New therapies for major human diseases and conditions, and new approaches for therapy taken further in the development pipeline” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” custom_margin=”|||” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(10,3,3,0.06)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

A AMELIE abre caminho a tratamentos inovadores id\u00eanticos ou semelhantes utilizando combina\u00e7\u00f5es de c\u00e9lulas-microtransportadoras ASMDC para uma variedade de outras condi\u00e7\u00f5es cl\u00ednicas associadas \u00e0 perda de fun\u00e7\u00e3o do m\u00fasculo esquel\u00e9tico, como a incontin\u00eancia urin\u00e1ria, as distrofias musculares e a perda volum\u00e9trica do m\u00fasculo associada a les\u00f5es traum\u00e1ticas.\u00a0<\/span><\/p>\n

O mesmo racioc\u00ednio cient\u00edfico e a nova abordagem desenvolvida no AMELIE s\u00e3o igualmente aplic\u00e1veis a outros tipos de c\u00e9lulas dependentes de ancoragem investigados como novos tratamentos de medicina regenerativa. Os novos produtos compostos por estas c\u00e9lulas dependentes de ancoragem destinam-se a tratar algumas das doen\u00e7as mais debilitantes que afectam os tecidos muscular, \u00f3sseo, cartilaginoso, ocular, card\u00edaco\/cardiovascular, gastrointestinal\/f\u00edgado, renal, imunit\u00e1rio e respirat\u00f3rio. A ado\u00e7\u00e3o da tecnologia de microcarreadores TIPS implant\u00e1veis poder\u00e1 ter um impacto significativo nos seus resultados.<\/span><\/p>\n

Entretanto, o processo de fabrico em escala para micropart\u00edculas TIPS desenvolvido pode ser aplicado a outras utiliza\u00e7\u00f5es da tecnologia de micropart\u00edculas que est\u00e3o atualmente a ser investigadas na linha de desenvolvimento. <\/span><\/p>\n

[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"

\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t
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BENEF\u00cdCIOS<\/h1><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
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DE AMELIE<\/h2><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t
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\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\"\"<\/span>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Identifica\u00e7\u00e3o de potenciais novas terapias regenerativas para responder a necessidades cl\u00ednicas n\u00e3o satisfeitas de grandes grupos de doentes.
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t
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\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\"\"<\/span>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>A posi\u00e7\u00e3o da Europa no dom\u00ednio da medicina regenerativa translacional foi refor\u00e7ada.
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t
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\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\"\"<\/span>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>New therapies for major human diseases and conditions, and new approaches for therapy taken further in the development pipeline.Faecal incontinence is a common condition affecting approximately 9% of adults in Europe. However, this figure is likely underestimated, as around 70% of individuals do not seek medical advice. Of those who do consult a healthcare professional, only a proportion pursue further treatment, and approximately half are not suitable for currently available options. The AMELIE approach offers several advantages over existing surgical interventions, which can carry risks such as infection, pain, and device failure or dislocation, sometimes resulting in the need for a permanent stoma. Improved continence outcomes have the potential to benefit not only patients, but also carers and […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-28371","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/28371","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/comments?post=28371"}],"version-history":[{"count":54,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/28371\/revisions"}],"predecessor-version":[{"id":31787,"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/pages\/28371\/revisions\/31787"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/pt\/wp-json\/wp\/v2\/media?parent=28371"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}