{"id":28691,"date":"2020-09-05T00:19:04","date_gmt":"2020-09-05T00:19:04","guid":{"rendered":"https:\/\/amelie-project.eu\/?page_id=28691"},"modified":"2026-07-01T10:07:51","modified_gmt":"2026-07-01T10:07:51","slug":"visione-e-obiettivi","status":"publish","type":"page","link":"https:\/\/amelie-project.eu\/it\/visione-e-obiettivi\/","title":{"rendered":"Visione e obiettivi"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”Hero section” _builder_version=”4.16″ _module_preset=”ac17d3a6-8373-45ed-95ce-70484e82a9b6″ use_background_color_gradient=”off” saved_tabs=”all” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.16″ _module_preset=”default” width=”100%” module_alignment=”left” custom_padding=”|||4%|false|false” custom_padding_tablet=”|||6%|false|false” custom_padding_phone=”|||7%|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][dsm_block_reveal_text block_reveal_text=”VISION” heading_html_tag=”h1″ block_reveal_color=”#0e94f9″ block_reveal_delay=”0″ _builder_version=”4.16″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”4vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”8vw” header_font_size_phone=”10vw” header_font_size_last_edited=”on|desktop” global_colors_info=”{}”][\/dsm_block_reveal_text][dsm_block_reveal_text block_reveal_text=”AND OBJECTIVES” block_reveal_color=”#0e94f9″ _builder_version=”4.16″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”3vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”5vw” header_font_size_phone=”6vw” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/dsm_block_reveal_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Features” _builder_version=”4.16″ background_enable_color=”off” custom_padding=”100px|0px|100px|0px||” global_colors_info=”{}”][et_pb_row column_structure=”1_3,1_3,1_3″ admin_label=”Sending Payments” _builder_version=”4.16″ max_width=”1440px” custom_margin=”|||” use_custom_width=”on” custom_width_px=”1440px” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/shutterstock_1069097789-Converted-1.png” title_text=”shutterstock_1069097789 %91Converted%93″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”10%” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.16″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.8em” header_font=”||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_color=”#000000″ header_2_font_size=”32px” header_2_line_height=”1.3em” header_3_font=”||||||||” header_4_font=”||||||||” text_orientation=”center” global_colors_info=”{}”]<\/p>\n

La nostra missione<\/h2>\n

Il consorzio sta sperimentando un nuovo approccio traslazionale alla produzione e alla somministrazione di cellule dipendenti dall\u2019ancoraggio. Consentendo l\u2019impianto delle cellule mentre queste rimangono attaccate a uno scaffold di supporto, questa tecnologia ha il potenziale di migliorare le terapie di medicina rigenerativa per l\u2019incontinenza fecale e molte altre applicazioni cliniche.<\/span><\/p>\n

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Il bisogno insoddisfatto<\/h2>\n
L'incontinenza fecale colpisce oltre 67 milioni di persone in tutta Europa, rappresentando una sfida per la salute pubblica diffusa ma poco riconosciuta.<\/div>\n
Sebbene non sia pericolosa per la vita, \u00e8 classificata dall\u2019Organizzazione Mondiale della Sanit\u00e0 (OMS) come una malattia che pu\u00f2 avere un impatto profondo su qualit\u00e0 della vita, <\/span>funzionamento quotidiano, <\/span>produttivit\u00e0, e <\/span>sistemi sanitari.<\/span><\/div>\n
Nonostante la sua diffusione, le attuali opzioni terapeutiche rimangono limitate. Spesso sono invasive, non adatte a tutti i pazienti o non garantiscono benefici duraturi a lungo termine, creando cos\u00ec un\u2019importante esigenza clinica non soddisfatta.<\/div>\n

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La nostra visione<\/h2>\n

AMELIE sta sviluppando un nuovo prodotto di ingegneria tissutale, classificato come medicinale per terapie avanzate combinate, in cui cellule dipendenti dall\u2019ancoraggio vengono fissate a un microvettore impiantabile, biodegradabile e clinicamente qualificato, con l\u2019obiettivo di migliorare direttamente i sintomi clinici dell\u2019incontinenza fecale.<\/span><\/p>\n

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Obiettivi AMELIE<\/h2>\n

[\/et_pb_text][et_pb_blurb title=”Objective 1:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1093px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Stabilire nuovi processi robusti per la produzione, la caratterizzazione, il trasporto e la consegna di microcarrier biodegradabili e impiantabili.<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 2:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Dimostrare la sicurezza dei microcarrier ASMDC utilizzando test non clinici per soddisfare i requisiti normativi nazionali e creare una sintesi del prodotto che consenta la valutazione della tecnologia in tutta Europa.<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 3:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1127px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Condurre uno studio paneuropeo randomizzato, in doppio cieco, per determinare se i microcarrier portano a una riduzione della frequenza degli episodi di FI.<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 4:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Coinvolgere le societ\u00e0 nazionali e regionali con il supporto di enti di beneficenza europei, reti di supporto ai pazienti e pubblico per stabilire canali per l'attivit\u00e0 di PPI e la diffusione degli sviluppi del progetto ai pazienti, al pubblico e alla comunit\u00e0 scientifica.<\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 5:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1051px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|25px|40px|false|false” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Sviluppare un piano aziendale e una strategia di commercializzazione futura per consentire l'accesso dei pazienti al microcarrier in Europa e nel mondo.<\/span><\/p>\n

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VISIONE<\/h1><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
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E OBIETTIVI<\/h2><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Our Mission The consortium is pioneering a novel translational approach to the manufacture and delivery of anchorage-dependent cells. By enabling cells to be implanted while remaining attached to a supportive scaffold, this technology has the potential to improve regenerative medicine therapies for faecal incontinence and many other clinical applications.The Unmet Need Faecal incontinence affects more than 67 million people across Europe, representing a common but under-recognised public health challenge. Although not life-threatening, it is classified by the World Health Organisation (WHO) as a disease that can have a profound impact on quality of life, daily functioning, productivity, and healthcare systems. Despite its prevalence, current treatment options remain limited. They are often invasive, not suitable for all patients, or fail to provide durable long-term benefit, creating a significant unmet clinical need.Our Vision AMELIE is developing a novel tissue-engineered product, classified as a combined advanced therapy medicinal product, in which anchorage-dependent cells are attached to an implantable, biodegradable and clinically qualified microcarrier with the aim of directly improving the […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-28691","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/it\/wp-json\/wp\/v2\/pages\/28691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/it\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/amelie-project.eu\/it\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/it\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/it\/wp-json\/wp\/v2\/comments?post=28691"}],"version-history":[{"count":42,"href":"https:\/\/amelie-project.eu\/it\/wp-json\/wp\/v2\/pages\/28691\/revisions"}],"predecessor-version":[{"id":31779,"href":"https:\/\/amelie-project.eu\/it\/wp-json\/wp\/v2\/pages\/28691\/revisions\/31779"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/it\/wp-json\/wp\/v2\/media?parent=28691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}