{"id":28691,"date":"2020-09-05T00:19:04","date_gmt":"2020-09-05T00:19:04","guid":{"rendered":"https:\/\/amelie-project.eu\/?page_id=28691"},"modified":"2026-07-01T10:07:51","modified_gmt":"2026-07-01T10:07:51","slug":"vision-et-objectifs","status":"publish","type":"page","link":"https:\/\/amelie-project.eu\/fr\/vision-et-objectifs\/","title":{"rendered":"Vision et objectifs"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”Hero section” _builder_version=”4.16″ _module_preset=”ac17d3a6-8373-45ed-95ce-70484e82a9b6″ use_background_color_gradient=”off” saved_tabs=”all” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.16″ _module_preset=”default” width=”100%” module_alignment=”left” custom_padding=”|||4%|false|false” custom_padding_tablet=”|||6%|false|false” custom_padding_phone=”|||7%|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][dsm_block_reveal_text block_reveal_text=”VISION” heading_html_tag=”h1″ block_reveal_color=”#0e94f9″ block_reveal_delay=”0″ _builder_version=”4.16″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”4vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”8vw” header_font_size_phone=”10vw” header_font_size_last_edited=”on|desktop” global_colors_info=”{}”][\/dsm_block_reveal_text][dsm_block_reveal_text block_reveal_text=”AND OBJECTIVES” block_reveal_color=”#0e94f9″ _builder_version=”4.16″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”3vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”5vw” header_font_size_phone=”6vw” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/dsm_block_reveal_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Features” _builder_version=”4.16″ background_enable_color=”off” custom_padding=”100px|0px|100px|0px||” global_colors_info=”{}”][et_pb_row column_structure=”1_3,1_3,1_3″ admin_label=”Sending Payments” _builder_version=”4.16″ max_width=”1440px” custom_margin=”|||” use_custom_width=”on” custom_width_px=”1440px” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/shutterstock_1069097789-Converted-1.png” title_text=”shutterstock_1069097789 %91Converted%93″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”10%” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.16″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.8em” header_font=”||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_color=”#000000″ header_2_font_size=”32px” header_2_line_height=”1.3em” header_3_font=”||||||||” header_4_font=”||||||||” text_orientation=”center” global_colors_info=”{}”]<\/p>\n

Notre mission<\/h2>\n

Ce consortium est \u00e0 l'origine d'une approche translationnelle novatrice en mati\u00e8re de fabrication et d'administration de cellules d\u00e9pendantes d'un ancrage. En permettant l'implantation de cellules tout en les maintenant fix\u00e9es \u00e0 une structure de soutien, cette technologie pourrait am\u00e9liorer les traitements de m\u00e9decine r\u00e9g\u00e9n\u00e9rative destin\u00e9s \u00e0 lutter contre l'incontinence f\u00e9cale, ainsi que de nombreuses autres applications cliniques.<\/span><\/p>\n

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Les besoins non satisfaits<\/h2>\n
L'incontinence f\u00e9cale touche plus de 67 millions de personnes en Europe, ce qui repr\u00e9sente un probl\u00e8me de sant\u00e9 publique courant mais souvent m\u00e9connu.<\/div>\n
Bien qu'elle ne mette pas la vie en danger, elle est class\u00e9e par l'Organisation mondiale de la sant\u00e9 (OMS) parmi les maladies pouvant avoir un impact consid\u00e9rable sur qualit\u00e9 de vie, <\/span>fonctionnement quotidien, <\/span>la productivit\u00e9, et <\/span>syst\u00e8mes de sant\u00e9.<\/span><\/div>\n
Malgr\u00e9 sa pr\u00e9valence, les options th\u00e9rapeutiques actuelles restent limit\u00e9es. Elles sont souvent invasives, ne conviennent pas \u00e0 tous les patients ou ne permettent pas d'obtenir des b\u00e9n\u00e9fices durables \u00e0 long terme, ce qui cr\u00e9e un besoin clinique important non satisfait.<\/div>\n

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Notre vision<\/h2>\n

AMELIE d\u00e9veloppe un produit innovant issu de l'ing\u00e9nierie tissulaire, class\u00e9 comme m\u00e9dicament de th\u00e9rapie innovante combin\u00e9e, dans lequel des cellules d\u00e9pendantes de l'ancrage sont fix\u00e9es \u00e0 un micro-support implantable, biod\u00e9gradable et cliniquement valid\u00e9, dans le but d'am\u00e9liorer directement les sympt\u00f4mes cliniques de l'incontinence f\u00e9cale.<\/span><\/p>\n

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Objectifs d'AMELIE<\/h2>\n

[\/et_pb_text][et_pb_blurb title=”Objective 1:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1093px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

\u00c9tablir de nouveaux processus robustes pour la fabrication, la caract\u00e9risation, le transport et l'administration de microporteurs biod\u00e9gradables et implantables.<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 2:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

D\u00e9montrer l'innocuit\u00e9 des microporteurs ASMDC \u00e0 l'aide de tests non cliniques afin de se conformer aux exigences r\u00e9glementaires nationales et cr\u00e9er un r\u00e9sum\u00e9 du produit qui permettra l'\u00e9valuation de la technologie dans toute l'Europe.<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 3:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1127px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Mener un essai paneurop\u00e9en randomis\u00e9 en double aveugle pour d\u00e9terminer si les microporteurs entra\u00eenent une r\u00e9duction de la fr\u00e9quence des \u00e9pisodes d'IF.<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 4:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Impliquer les soci\u00e9t\u00e9s nationales et r\u00e9gionales avec le soutien des associations caritatives europ\u00e9ennes, des r\u00e9seaux de soutien aux patients et du public afin d'\u00e9tablir des canaux pour l'activit\u00e9 PPI et la diffusion des d\u00e9veloppements du projet aupr\u00e8s des patients, du public et de la communaut\u00e9 scientifique.<\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 5:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1051px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|25px|40px|false|false” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

D\u00e9velopper un plan d'affaires et une strat\u00e9gie de commercialisation future pour permettre l'acc\u00e8s des patients \u00e0 la microporteuse \u00e0 travers l'Europe et le monde.<\/span><\/p>\n

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VISION<\/h1><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
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ET OBJECTIFS<\/h2><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Our Mission The consortium is pioneering a novel translational approach to the manufacture and delivery of anchorage-dependent cells. By enabling cells to be implanted while remaining attached to a supportive scaffold, this technology has the potential to improve regenerative medicine therapies for faecal incontinence and many other clinical applications.The Unmet Need Faecal incontinence affects more than 67 million people across Europe, representing a common but under-recognised public health challenge. Although not life-threatening, it is classified by the World Health Organisation (WHO) as a disease that can have a profound impact on quality of life, daily functioning, productivity, and healthcare systems. Despite its prevalence, current treatment options remain limited. They are often invasive, not suitable for all patients, or fail to provide durable long-term benefit, creating a significant unmet clinical need.Our Vision AMELIE is developing a novel tissue-engineered product, classified as a combined advanced therapy medicinal product, in which anchorage-dependent cells are attached to an implantable, biodegradable and clinically qualified microcarrier with the aim of directly improving the […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-28691","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages\/28691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/comments?post=28691"}],"version-history":[{"count":42,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages\/28691\/revisions"}],"predecessor-version":[{"id":31779,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages\/28691\/revisions\/31779"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/media?parent=28691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}