{"id":28691,"date":"2020-09-05T00:19:04","date_gmt":"2020-09-05T00:19:04","guid":{"rendered":"https:\/\/amelie-project.eu\/?page_id=28691"},"modified":"2021-01-25T12:42:37","modified_gmt":"2021-01-25T12:42:37","slug":"vision-et-objectifs","status":"publish","type":"page","link":"https:\/\/amelie-project.eu\/fr\/vision-et-objectifs\/","title":{"rendered":"Vision et objectifs"},"content":{"rendered":"[et_pb_section fb_built=”1″ admin_label=”Hero section” _builder_version=”4.6.3″ _module_preset=”ac17d3a6-8373-45ed-95ce-70484e82a9b6″ use_background_color_gradient=”off” saved_tabs=”all”][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.6.3″ _module_preset=”default” width=”100%” module_alignment=”left” custom_padding=”|||4%|false|false” custom_padding_tablet=”|||6%|false|false” custom_padding_phone=”|||7%|false|false”][et_pb_column type=”4_4″ _builder_version=”4.6.3″ _module_preset=”default”][dsm_block_reveal_text block_reveal_text=”VISION” heading_html_tag=”h1″ block_reveal_color=”#0e94f9″ block_reveal_delay=”0″ _builder_version=”4.6.3″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”4vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”8vw” header_font_size_phone=”10vw” header_font_size_last_edited=”on|desktop”][\/dsm_block_reveal_text][dsm_block_reveal_text block_reveal_text=”AND OBJECTIVES” block_reveal_color=”#0e94f9″ _builder_version=”4.6.3″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”3vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”5vw” header_font_size_phone=”6vw” header_font_size_last_edited=”on|phone”][\/dsm_block_reveal_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Features” _builder_version=”4.6.3″ background_enable_color=”off” custom_padding=”100px|0px|100px|0px||”][et_pb_row column_structure=”1_3,1_3,1_3″ admin_label=”Sending Payments” _builder_version=”3.25″ max_width=”1440px” custom_margin=”|||” use_custom_width=”on” custom_width_px=”1440px”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/shutterstock_1069097789-Converted-1.png” title_text=”shutterstock_1069097789 %91Converted%93″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.6.3″ animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”10%”][\/et_pb_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_font_size=”16px” text_line_height=”1.8em” header_font=”||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_color=”#000000″ header_2_font_size=”32px” header_2_line_height=”1.3em” header_3_font=”||||||||” header_4_font=”||||||||” text_orientation=”center” hover_enabled=”0″ sticky_enabled=”0″ text_text_color=”#000000″]

Notre mission<\/h2>\n

Le consortium propose une approche translationnelle radicale et innovante pour fabriquer et d\u00e9livrer des cellules d\u00e9pendantes de l'ancrage dans l'organisme, sous la forme d'une nouvelle th\u00e9rapie cellulaire, afin d'\u00e9tablir des th\u00e9rapies de m\u00e9decine r\u00e9g\u00e9n\u00e9rative plus efficaces pour l'IF et d'autres indications cliniques.<\/p>[\/et_pb_text][et_pb_button button_url=”\/approach\/” button_text=”LEARN MORE” button_alignment=”center” _builder_version=”4.6.3″ _module_preset=”default” custom_button=”on” button_text_size=”12px” button_text_color=”#000000″ button_bg_color=”#ffffff” button_border_width=”1px” button_border_color=”#000000″ button_border_radius=”5px” button_letter_spacing=”2px” button_font=”Gotham kinda bold|600||on|||||” button_icon=”%%20%%” button_icon_color=”#000000″ button_on_hover=”off” custom_margin=”-17px||||false|false” custom_padding=”12px|30px|12px|20px|false|false” animation_style=”fold” animation_duration=”850ms” animation_intensity_fold=”16%” hover_enabled=”0″ button_letter_spacing_tablet=”” button_letter_spacing_phone=”1px” button_letter_spacing_last_edited=”on|phone” button_bg_color__hover=”#0c71c3″ button_bg_color__hover_enabled=”on|desktop” button_border_color__hover=”rgba(0,0,0,0)” button_border_color__hover_enabled=”on|desktop” button_letter_spacing__hover=”2px” button_letter_spacing__hover_enabled=”off|desktop” box_shadow_vertical_button__hover=”8px” box_shadow_vertical_button__hover_enabled=”on|hover” box_shadow_color__hover_enabled=”on|hover” box_shadow_color__hover=”rgba(7,82,140,0.54)” box_shadow_vertical__hover_enabled=”on|desktop” box_shadow_vertical__hover=”10px” button_bg_enable_color__hover=”on” button_text_color__hover_enabled=”on|desktop” button_text_color__hover=”#ffffff” button_border_width__hover_enabled=”on|hover” button_border_width__hover=”1px” button_icon_color__hover_enabled=”on|desktop” button_icon_color__hover=”#ffffff” sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/shutterstock_1289992183-Converted-1.png” title_text=”shutterstock_1289992183 %91Converted%93″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.6.3″ width=”210px” custom_margin=”60px|||” animation_style=”slide” animation_direction=”bottom” animation_delay=”200ms” animation_intensity_slide=”10%” locked=”off”][\/et_pb_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_font_size=”16px” text_line_height=”1.8em” header_font=”||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_color=”#000000″ header_2_font_size=”32px” header_2_line_height=”1.3em” header_3_font=”||||||||” header_4_font=”||||||||” text_orientation=”center” locked=”off” text_text_color=”#000000″ hover_enabled=”0″ sticky_enabled=”0″]

La condition<\/h2>\n

L'incontinence f\u00e9cale est une affection courante. Bien qu'elle ne mette pas la vie en danger, elle est class\u00e9e comme une maladie par l'Organisation mondiale de la sant\u00e9 (OMS), entravant gravement la vie quotidienne et la productivit\u00e9 des personnes touch\u00e9es et de leurs familles, et faisant peser une charge substantielle sur les services de sant\u00e9 europ\u00e9ens. Il existe un besoin th\u00e9rapeutique particulier non satisfait pour les patients pr\u00e9sentant des sympt\u00f4mes s\u00e9v\u00e8res d'incontinence f\u00e9cale (IF), qui ne sont pas aptes ou ne souhaitent pas subir les options chirurgicales actuellement disponibles, mais qui pourraient b\u00e9n\u00e9ficier d'une approche m\u00e9dicale r\u00e9g\u00e9n\u00e9ratrice.<\/p>[\/et_pb_text][et_pb_button button_url=”\/our-research\/” button_text=”LEARN MORE” button_alignment=”center” _builder_version=”4.6.3″ _module_preset=”default” custom_button=”on” button_text_size=”12px” button_text_color=”#000000″ button_bg_color=”#ffffff” button_border_width=”1px” button_border_color=”#000000″ button_border_radius=”5px” button_letter_spacing=”2px” button_font=”Gotham kinda bold|600||on|||||” button_icon=”%%20%%” button_icon_color=”#000000″ button_on_hover=”off” custom_margin=”-17px||||false|false” custom_padding=”12px|30px|12px|20px|false|false” animation_style=”fold” animation_duration=”850ms” animation_intensity_fold=”16%” button_letter_spacing_tablet=”” button_letter_spacing_phone=”1px” button_letter_spacing_last_edited=”on|phone” button_bg_color__hover=”#0c71c3″ button_bg_color__hover_enabled=”on|desktop” button_border_color__hover=”rgba(0,0,0,0)” button_border_color__hover_enabled=”on|desktop” button_letter_spacing__hover=”2px” button_letter_spacing__hover_enabled=”on|desktop” box_shadow_vertical_button__hover=”8px” box_shadow_vertical_button__hover_enabled=”on|hover” box_shadow_color__hover_enabled=”on|hover” box_shadow_color__hover=”rgba(7,82,140,0.54)” box_shadow_vertical__hover_enabled=”on|desktop” box_shadow_vertical__hover=”10px” button_text_color__hover=”#ffffff” button_text_color__hover_enabled=”on|desktop” button_border_width__hover=”1px” button_border_width__hover_enabled=”on|hover” button_icon_color__hover=”#ffffff” button_icon_color__hover_enabled=”on|desktop”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/12\/shutterstock_1069097789-Converted.png” title_text=”shutterstock_1069097789 %91Converted%93″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.6.3″ custom_padding=”||||false|false” custom_padding_tablet=”50px||||false|false” custom_padding_phone=”” custom_padding_last_edited=”on|desktop” animation_style=”slide” animation_direction=”bottom” animation_duration=”100ms” animation_intensity_slide=”10%”][\/et_pb_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_font_size=”16px” text_line_height=”1.8em” header_font=”||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_color=”#000000″ header_2_font_size=”32px” header_2_line_height=”1.3em” header_3_font=”||||||||” header_4_font=”||||||||” text_orientation=”center” locked=”off” text_text_color=”#000000″]

Notre vision<\/h2>\n

AMELIE d\u00e9veloppera un nouveau produit d'ing\u00e9nierie tissulaire (m\u00e9dicament combin\u00e9 de th\u00e9rapie avanc\u00e9e) qui comprend la fixation de cellules d\u00e9pendantes de l'ancrage \u00e0 un microporteur implantable biod\u00e9gradable, cliniquement qualifi\u00e9, afin d'am\u00e9liorer directement les sympt\u00f4mes cliniques de l'IF.<\/p>[\/et_pb_text][et_pb_button button_url=”\/engagement-activities\/” button_text=”LEARN MORE” button_alignment=”center” _builder_version=”4.6.3″ _module_preset=”default” custom_button=”on” button_text_size=”12px” button_text_color=”#000000″ button_bg_color=”#ffffff” button_border_width=”1px” button_border_color=”#000000″ button_border_radius=”5px” button_letter_spacing=”2px” button_font=”Gotham kinda bold|600||on|||||” button_icon=”%%20%%” button_icon_color=”#000000″ button_on_hover=”off” custom_margin=”-17px||||false|false” custom_padding=”12px|30px|12px|20px|false|false” animation_style=”fold” animation_duration=”850ms” animation_intensity_fold=”16%” button_letter_spacing_tablet=”” button_letter_spacing_phone=”1px” button_letter_spacing_last_edited=”on|phone” button_bg_color__hover=”#0c71c3″ button_bg_color__hover_enabled=”on|desktop” button_border_color__hover=”rgba(0,0,0,0)” button_border_color__hover_enabled=”on|desktop” button_letter_spacing__hover=”2px” button_letter_spacing__hover_enabled=”on|desktop” box_shadow_vertical_button__hover=”8px” box_shadow_vertical_button__hover_enabled=”on|hover” box_shadow_color__hover_enabled=”on|hover” box_shadow_color__hover=”rgba(7,82,140,0.54)” box_shadow_vertical__hover_enabled=”on|desktop” box_shadow_vertical__hover=”10px” button_text_color__hover=”#ffffff” button_text_color__hover_enabled=”on|desktop” button_border_width__hover=”1px” button_border_width__hover_enabled=”on|hover” button_icon_color__hover=”#ffffff” button_icon_color__hover_enabled=”on|desktop”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Stats and Features” _builder_version=”3.22″ background_color=”#f7f8fc” custom_padding=”80px|0px|54px|0px|false|false”][et_pb_row use_custom_gutter=”on” gutter_width=”4″ _builder_version=”4.6.3″ custom_margin=”||||false|false” custom_padding=”0px|||”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” parallax__hover=”off” parallax_method__hover=”on” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.6.3″ _module_preset=”default” header_font=”Gotham||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_align=”center” header_2_text_color=”#000000″ header_2_font_size=”5vh” header_2_line_height=”1.2em” hover_enabled=”0″ sticky_enabled=”0″]

Objectifs d'AMELIE<\/h2>[\/et_pb_text][et_pb_blurb title=”Objective 1:” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1093px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” locked=”off” sticky_enabled=”0″]

\u00c9tablir de nouveaux processus robustes pour la fabrication, la caract\u00e9risation, le transport et l'administration de microporteurs biod\u00e9gradables et implantables.<\/span><\/p>[\/et_pb_blurb][et_pb_blurb title=”Objective 2:” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” locked=”off” sticky_enabled=”0″]

D\u00e9montrer l'innocuit\u00e9 des microporteurs ASMDC \u00e0 l'aide de tests non cliniques afin de se conformer aux exigences r\u00e9glementaires nationales et cr\u00e9er un r\u00e9sum\u00e9 du produit qui permettra l'\u00e9valuation de la technologie dans toute l'Europe.<\/span><\/p>[\/et_pb_blurb][et_pb_blurb title=”Objective 3:” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1127px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” locked=”off” sticky_enabled=”0″]

Mener un essai paneurop\u00e9en randomis\u00e9 en double aveugle pour d\u00e9terminer si les microporteurs entra\u00eenent une r\u00e9duction de la fr\u00e9quence des \u00e9pisodes d'IF.<\/span><\/p>[\/et_pb_blurb][et_pb_blurb title=”Objective 4:” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” locked=”off” sticky_enabled=”0″]

Impliquer les soci\u00e9t\u00e9s nationales et r\u00e9gionales avec le soutien des associations caritatives europ\u00e9ennes, des r\u00e9seaux de soutien aux patients et du public afin d'\u00e9tablir des canaux pour l'activit\u00e9 PPI et la diffusion des d\u00e9veloppements du projet aupr\u00e8s des patients, du public et de la communaut\u00e9 scientifique.<\/p>[\/et_pb_blurb][et_pb_blurb title=”Objective 5:” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1051px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|25px|40px|false|false” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” locked=”off” sticky_enabled=”0″]

D\u00e9velopper un plan d'affaires et une strat\u00e9gie de commercialisation future pour permettre l'acc\u00e8s des patients \u00e0 la microporteuse \u00e0 travers l'Europe et le monde.<\/span><\/p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.6.3″ _module_preset=”default”][\/et_pb_section]","protected":false},"excerpt":{"rendered":"

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VISION<\/h1><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
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ET OBJECTIFS<\/h2><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Our Mission The consortium proposes a radical, innovative translational approach to manufacture and deliver anchorage-dependent cells into the body, as a form of new cell therapy, to establish more effective regenerative medicine therapies for FI and other clinical indications.The Condition Faecal incontinence is a common condition. Whilst not life threatening, it is classified as a disease by the World Health Organization (WHO), seriously impairing daily living and productivity of affected individuals and their families, and resulting in a substantial burden on European health services. There is a particular therapeutic unmet need for patients with severe symptoms of faecal incontinence (FI), who are either unsuitable for, or do not wish to undergo, currently available surgical options, but who may benefit from a regenerative medical approach.Our Vision AMELIE will develop a novel tissue engineered product (combined advanced therapy medicinal product) that comprises attaching the anchorage dependent cells to an implantable biodegradable, clinically qualified microcarrier so as to directly improve the clinical symptoms of FI.AMELIE ObjectivesEstablish new robust processes for the manufacturing, […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-28691","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages\/28691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/comments?post=28691"}],"version-history":[{"count":38,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages\/28691\/revisions"}],"predecessor-version":[{"id":31170,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages\/28691\/revisions\/31170"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/media?parent=28691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}