{"id":28371,"date":"2020-09-03T09:02:33","date_gmt":"2020-09-03T09:02:33","guid":{"rendered":"https:\/\/amelie-project.eu\/?page_id=28371"},"modified":"2021-01-26T10:47:43","modified_gmt":"2021-01-26T10:47:43","slug":"avantages-damelie","status":"publish","type":"page","link":"https:\/\/amelie-project.eu\/fr\/avantages-damelie\/","title":{"rendered":"Avantages d'AMELIE"},"content":{"rendered":"[et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” disabled_on=”off|off|off” admin_label=”Hero section” _builder_version=”4.6.3″ background_image=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/AMELIEHEADERBACKGOUND-01-scaled.jpg” background_position=”center_left” custom_margin=”|||” custom_padding=”7%||7%||true|false” custom_padding_tablet=”15%||15%||true|false” custom_padding_phone=””][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.6.3″ _module_preset=”default” width=”100%” module_alignment=”left” custom_padding=”|||4%|false|false” custom_padding_tablet=”|||6%|false|false” custom_padding_phone=”|||7%|false|false”][et_pb_column type=”4_4″ _builder_version=”4.6.3″ _module_preset=”default”][dsm_block_reveal_text block_reveal_text=”BENEFITS” heading_html_tag=”h1″ block_reveal_color=”#0e94f9″ block_reveal_delay=”0″ _builder_version=”4.6.3″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”4vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”8vw” header_font_size_phone=”10vw” header_font_size_last_edited=”on|desktop”][\/dsm_block_reveal_text][dsm_block_reveal_text block_reveal_text=”OF AMELIE” block_reveal_color=”#0e94f9″ _builder_version=”4.6.3″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”3vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”6vw” header_font_size_phone=”7vw” header_font_size_last_edited=”on|desktop”][\/dsm_block_reveal_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.6.3″ transform_scale_tablet=”90%|90%” transform_scale_last_edited=”off|desktop” transform_translate_last_edited=”off|desktop” transform_rotate_last_edited=”off|desktop” transform_skew_last_edited=”off|desktop” transform_origin_last_edited=”off|desktop” transform_styles_last_edited=”off|desktop” custom_margin=”||||false|false” custom_padding=”100px|0px|100px|0px” custom_padding_tablet=”35px|0px|35px|0px|true|false” custom_padding_phone=”15px||15px||true|false”][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.6.3″ _module_preset=”default” animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”11%”][et_pb_column type=”1_3″ _builder_version=”4.6.3″ _module_preset=”default”][dsm_tilt_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/09\/science1shadow-4.png” title_text=”science1shadow” dsm_tilt_mobile=”on” dsm_tilt_scale=”1.1″ dsm_tilt_max=”15″ dsm_use_glare=”on” dsm_tilt_glare=”0.5″ _builder_version=”4.6.3″ _module_preset=”default”][\/dsm_tilt_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.6em” header_font=”Gotham kinda bold|||on|||||” header_text_color=”#000000″ header_font_size=”15px” header_letter_spacing=”1px” header_line_height=”1.4em” header_2_font=”Gotham kinda bold|||on|||||” header_2_text_color=”#000000″ header_2_font_size=”15px” header_2_letter_spacing=”1px” header_2_line_height=”1.4em” header_3_font=”Gotham kinda bold|||on|||||” header_3_text_color=”#000000″ header_3_font_size=”15px” header_3_letter_spacing=”1px” header_3_line_height=”1.4em” header_4_font=”Gotham kinda bold|||on|||||” header_4_text_color=”#000000″ header_4_font_size=”17px” header_4_letter_spacing=”1px” header_4_line_height=”1.4em” header_5_font=”Gotham kinda bold|||on|||||” header_5_text_color=”#000000″ header_5_font_size=”15px” header_5_letter_spacing=”1px” header_5_line_height=”1.4em” header_6_font=”Gotham kinda bold|||on|||||” header_6_text_color=”#000000″ header_6_font_size=”15px” header_6_letter_spacing=”1px” header_6_line_height=”1.4em” text_orientation=”center” max_width=”800px” module_alignment=”center” locked=”off”]

Identification de nouvelles th\u00e9rapies r\u00e9g\u00e9n\u00e9ratives potentielles pour r\u00e9pondre aux besoins cliniques non satisfaits de grands groupes de patients.<\/p>[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.6.3″ _module_preset=”default”][dsm_tilt_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/09\/science2shadow.png” title_text=”science2shadow” dsm_tilt_mobile=”on” dsm_tilt_scale=”1.1″ dsm_tilt_max=”15″ dsm_use_glare=”on” dsm_tilt_glare=”0.5″ _builder_version=”4.6.3″ _module_preset=”default”][\/dsm_tilt_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.6em” header_font=”Gotham kinda bold|||on|||||” header_text_color=”#000000″ header_font_size=”15px” header_letter_spacing=”1px” header_line_height=”1.4em” header_2_font=”Gotham kinda bold|||on|||||” header_2_text_color=”#000000″ header_2_font_size=”15px” header_2_letter_spacing=”1px” header_2_line_height=”1.4em” header_3_font=”Gotham kinda bold|||on|||||” header_3_text_color=”#000000″ header_3_font_size=”15px” header_3_letter_spacing=”1px” header_3_line_height=”1.4em” header_4_font=”Gotham kinda bold|||on|||||” header_4_text_color=”#000000″ header_4_font_size=”17px” header_4_letter_spacing=”1px” header_4_line_height=”1.4em” header_5_font=”Gotham kinda bold|||on|||||” header_5_text_color=”#000000″ header_5_font_size=”15px” header_5_letter_spacing=”1px” header_5_line_height=”1.4em” header_6_font=”Gotham kinda bold|||on|||||” header_6_text_color=”#000000″ header_6_font_size=”15px” header_6_letter_spacing=”1px” header_6_line_height=”1.4em” text_orientation=”center” max_width=”800px” module_alignment=”center” locked=”off”]

La position de l'Europe dans le domaine de la m\u00e9decine r\u00e9g\u00e9n\u00e9rative translationnelle s'est renforc\u00e9e.<\/p>[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.6.3″ _module_preset=”default”][dsm_tilt_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/09\/science3shadow-2.png” title_text=”science3shadow” dsm_tilt_mobile=”on” dsm_tilt_scale=”1.1″ dsm_tilt_max=”15″ dsm_use_glare=”on” dsm_tilt_glare=”0.5″ _builder_version=”4.6.3″ _module_preset=”default”][\/dsm_tilt_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.6em” header_font=”Gotham kinda bold|||on|||||” header_text_color=”#000000″ header_font_size=”15px” header_letter_spacing=”1px” header_line_height=”1.4em” header_2_font=”Gotham kinda bold|||on|||||” header_2_text_color=”#000000″ header_2_font_size=”15px” header_2_letter_spacing=”1px” header_2_line_height=”1.4em” header_3_font=”Gotham kinda bold|||on|||||” header_3_text_color=”#000000″ header_3_font_size=”15px” header_3_letter_spacing=”1px” header_3_line_height=”1.4em” header_4_font=”Gotham kinda bold|||on|||||” header_4_text_color=”#000000″ header_4_font_size=”17px” header_4_letter_spacing=”1px” header_4_line_height=”1.4em” header_5_font=”Gotham kinda bold|||on|||||” header_5_text_color=”#000000″ header_5_font_size=”15px” header_5_letter_spacing=”1px” header_5_line_height=”1.4em” header_6_font=”Gotham kinda bold|||on|||||” header_6_text_color=”#000000″ header_6_font_size=”15px” header_6_letter_spacing=”1px” header_6_line_height=”1.4em” text_orientation=”center” max_width=”800px” module_alignment=”center” locked=”off”]

Nouvelles th\u00e9rapies pour les principales maladies et affections humaines, et nouvelles approches th\u00e9rapeutiques en cours de d\u00e9veloppement.<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ background_color=”rgba(0,0,0,0.03)” background_position=”top_center” custom_margin=”|||” custom_padding=”100px||100px|”][et_pb_row use_custom_gutter=”on” gutter_width=”4″ _builder_version=”4.6.3″ custom_margin=”||||false|false” custom_padding=”0px|||”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” parallax__hover=”off” parallax_method__hover=”on” custom_padding__hover=”|||”][et_pb_blurb title=”Potential new regenerative therapies to address unmet clinical needs of large patient groups identified” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” custom_margin=”|||” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(10,3,3,0.06)” locked=”off”]

L'IF est une affection courante qui touche ~9% adultes europ\u00e9ens. Ce chiffre est sous-estim\u00e9 car ~70% des patients atteints d'IF ne consultent pas un prestataire de soins de sant\u00e9 au sujet de leur \u00e9tat. Seule une partie d'entre eux cherchera \u00e0 se faire soigner, mais ~50% ne conviendront pas aux options actuelles. L'approche d'AMELIE pr\u00e9sente de nombreux avantages par rapport aux autres interventions chirurgicales, qui pr\u00e9sentent des risques d'infection, de douleur et de d\u00e9fectuosit\u00e9\/dislocation de la sonde, ce qui peut entra\u00eener une stomie permanente. L'am\u00e9lioration de la continence \u00e0 la suite du traitement aura un impact au-del\u00e0 des personnes souffrant imm\u00e9diatement de la maladie, comme les soignants et les personnes inscrites sur les listes d'attente des maisons de retraite.<\/span>\u00a0<\/span><\/p>\n

S'il est efficace, le traitement par la technologie des microporteurs cellulaires implantables aura un impact significatif sur la qualit\u00e9 de vie des citoyens de l'UE.<\/span> La promotion de ce traitement en tant qu'approche r\u00e9aliste pour <\/span>traiter<\/span><\/i> plut\u00f4t que de g\u00e9rer les sympt\u00f4mes, augmentera la probabilit\u00e9 que les patients atteints d'IF consultent un prestataire de soins de sant\u00e9 au sujet de leur \u00e9tat et augmentera donc le nombre de patients que le traitement peut atteindre.<\/span><\/p>[\/et_pb_blurb][et_pb_blurb title=”Europe\u2019s position in translational regenerative medicine strengthened ” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” custom_margin=”|||” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(10,3,3,0.06)” locked=”off” sticky_enabled=”0″]

L'Europe est \u00e0 la pointe des th\u00e9rapies cellulaires pour les patients atteints d'IF.<\/span> En plus de renforcer le r\u00f4le dominant de l'Europe dans ce domaine, AMELIE repr\u00e9sente \u00e9galement un changement radical dans l'approche adopt\u00e9e pour fabriquer et fournir des m\u00e9dicaments \u00e0 base de cellules qui permettront aux citoyens europ\u00e9ens d'\u00eatre les premiers au monde \u00e0 b\u00e9n\u00e9ficier d'une nouvelle approche pionni\u00e8re de la m\u00e9decine r\u00e9g\u00e9n\u00e9ratrice.\u00a0<\/span><\/p>\n

La th\u00e9rapie cellulaire est un domaine de recherche en pleine expansion. Les produits issus de l'ing\u00e9nierie tissulaire sont appel\u00e9s \u00e0 se d\u00e9velopper de mani\u00e8re significative et offrent d'importantes possibilit\u00e9s de renforcer la position de l'Europe dans le domaine de la m\u00e9decine r\u00e9g\u00e9n\u00e9rative translationnelle. L'Europe repr\u00e9sente environ 26% des entreprises mondiales de m\u00e9decine r\u00e9g\u00e9n\u00e9rative. Le d\u00e9veloppement de technologies innovantes telles que les microporteurs implantables TIPS attirera les investissements en Europe. AMELIE cherche ensuite \u00e0 am\u00e9liorer la position concurrentielle des entreprises europ\u00e9ennes en tant que fournisseurs de technologies innovantes pour la m\u00e9decine r\u00e9g\u00e9n\u00e9rative. Le potentiel d'exploitation d'AMELIE s'en trouvera renforc\u00e9.<\/span><\/p>\n[\/et_pb_blurb][et_pb_blurb title=”New therapies for major human diseases and conditions, and new approaches for therapy taken further in the development pipeline” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” custom_margin=”|||” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(10,3,3,0.06)” locked=”off”]

AMELIE ouvre la voie \u00e0 des traitements innovants identiques ou similaires utilisant des combinaisons de cellules ASMDC et de microporteurs pour une vari\u00e9t\u00e9 d'autres conditions cliniques associ\u00e9es \u00e0 la perte de la fonction musculaire squelettique, telles que l'incontinence urinaire, les dystrophies musculaires et la perte musculaire volum\u00e9trique associ\u00e9e \u00e0 un traumatisme.\u00a0<\/span><\/p>\n

Le m\u00eame raisonnement scientifique et la m\u00eame nouvelle approche d\u00e9velopp\u00e9s dans AMELIE sont \u00e9galement applicables \u00e0 d'autres types de cellules d\u00e9pendantes de l'ancrage \u00e9tudi\u00e9es comme nouveaux traitements de m\u00e9decine r\u00e9g\u00e9n\u00e9rative. Les nouveaux produits compos\u00e9s de ces cellules d\u00e9pendantes de l'ancrage sont destin\u00e9s \u00e0 traiter certaines des maladies les plus d\u00e9bilitantes qui affectent les muscles, les os, le cartilage, les tissus oculaires, cardiaques\/cardiovasculaires, gastro-intestinaux\/du foie, r\u00e9naux, immunitaires et respiratoires. L'adoption de la technologie des microporteurs implantables TIPS pourrait avoir un impact significatif sur leurs r\u00e9sultats.<\/span><\/p>\n

Entre-temps, le processus de fabrication \u00e0 grande \u00e9chelle des microparticules TIPS peut \u00eatre appliqu\u00e9 \u00e0 d'autres utilisations de la technologie des microparticules actuellement \u00e0 l'\u00e9tude dans le pipeline de d\u00e9veloppement. <\/span><\/p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.6.3″ _module_preset=”default”][\/et_pb_section]","protected":false},"excerpt":{"rendered":"

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B\u00c9N\u00c9FICES<\/h1><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
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D'AMELIE<\/h2><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
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\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\"\"<\/span>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Identification de nouvelles th\u00e9rapies r\u00e9g\u00e9n\u00e9ratives potentielles pour r\u00e9pondre aux besoins cliniques non satisfaits de grands groupes de patients.
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t
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\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\"\"<\/span>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>La position de l'Europe dans le domaine de la m\u00e9decine r\u00e9g\u00e9n\u00e9rative translationnelle s'est renforc\u00e9e.
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t
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\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\"\"<\/span>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>New therapies for major human diseases and conditions, and new approaches for therapy taken further in the development pipeline.FI is a common condition affecting ~9% European adults. This figure is underestimated as ~70% of patients with FI do not consult a healthcare provider about their condition. Only a proportion of those that do will seek further treatment, but ~50% will not be suited to current options. AMELIE\u2019s approach has numerous advantages over other surgical interventions, which risk infection, pain and lead defect\/dislocation, which can result in permanent stoma. The effect of improved continence following treatment will have impact beyond those immediately suffering the condition, such as carers and those on nursing home waiting lists.\u00a0 If effective, treatment with the implantable cell-microcarrier technology will […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-28371","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages\/28371","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/comments?post=28371"}],"version-history":[{"count":53,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages\/28371\/revisions"}],"predecessor-version":[{"id":31152,"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/pages\/28371\/revisions\/31152"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/fr\/wp-json\/wp\/v2\/media?parent=28371"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}