{"id":31461,"date":"2023-10-09T16:23:22","date_gmt":"2023-10-09T16:23:22","guid":{"rendered":"https:\/\/amelie-project.eu\/?post_type=publication&p=31461"},"modified":"2024-02-26T16:30:40","modified_gmt":"2024-02-26T16:30:40","slug":"publicacion-4","status":"publish","type":"publication","link":"https:\/\/amelie-project.eu\/es\/publicacion\/publicacion-4\/","title":{"rendered":"Construir anillos con esferas: un enfoque de terapia celular para la incontinencia"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.16″ global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row _builder_version=”4.21.0″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”post_content” width=”100%” sticky_enabled=”0″][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Martha Gilbert, Simona \u010caputov\u00e1, Delielena Poli, Manou Kooy, Georgia Sturt, Josephine Parker y Richard M Day.<\/strong><\/p>\n

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Cell & Gene Therapy Insights 2023; 9(10), 1293-1306.<\/p>\n

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La incontinencia fecal es una afecci\u00f3n prevalente de la que se informa muy poco. Esta afecci\u00f3n afecta a la calidad de vida de los pacientes y tiene un impacto socioecon\u00f3mico y medioambiental negativo en la sociedad. Las directrices actuales para el tratamiento de los pacientes recomiendan un enfoque gradual para tratar la incontinencia fecal, desde las opciones de tratamiento conservador, pasando por las opciones quir\u00fargicas m\u00ednimamente invasivas, hasta las opciones quir\u00fargicas de primera y segunda l\u00ednea. Por desgracia, los tratamientos conservadores siguen siendo ineficaces y, en muchos casos, las opciones quir\u00fargicas no son deseables o no son adecuadas. La medicina regenerativa, y en concreto la terapia celular, tiene el potencial de ofrecer un tratamiento curativo menos invasivo, m\u00e1s eficaz y eficiente. Las tecnolog\u00edas de terapia celular, aunque a\u00fan se encuentran en fase de desarrollo, pueden mejorar la situaci\u00f3n actual en el \u00e1mbito de la incontinencia fecal a nivel cl\u00ednico, del paciente y socioecon\u00f3mico. El objetivo de este art\u00edculo es doble. En primer lugar, concienciar sobre la afecci\u00f3n silenciosa que es la incontinencia fecal y sobre el impacto que tiene en los pacientes y en la sociedad. En segundo lugar, se trata de situar la terapia celular, en relaci\u00f3n con los enfoques terap\u00e9uticos actuales, incluyendo, por ejemplo, la estimulaci\u00f3n del nervio sacro y la esfinteroplastia, como para enfatizar su potencial para proporcionar una alternativa de tratamiento adecuada. <\/p>\n

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Acceda al documento completo aqu\u00ed:<\/p>\n

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https:\/\/www.insights.bio\/cell-and-gene-therapy-insights\/journal\/article\/3016\/Building-rings-with-spheres-a-cell-therapy-approach-to-incontinence<\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"

Martha Gilbert, Simona \u010caputov\u00e1, Delielena Poli, Manou Kooy, Georgia Sturt, Josephine Parker and Richard M Day. Cell & Gene Therapy Insights 2023; 9(10), 1293\u20131306. Fecal incontinence is a prevalent condition, that remains vastly underreported. The condition impacts the patients\u2019 quality of life and has negative socio-economic and environmental impact on the society. Current patient management guidelines recommend a stepwise approach to treating fecal incontinence, from conservative treatment options, through minimally invasive surgical options, all the way to first- and second-line surgical options. Unfortunately, the conservative treatments remain ineffective, and, in many cases, the surgical options are either not desirable or not suitable. Regenerative medicine, and specifically, cell therapy, has the potential to offer a curative treatment that is less invasive, more effective and efficient. Cell therapy technologies, while still under development, can improve the current state-of-play in the realm of fecal incontinence at the clinical, patient, and socio-economic level. The aim of this article is twofold. Firstly, it is to raise awareness about the silent affliction that fecal incontinence is and about the impact that it has on patients and society. Secondly, it is to position cell therapy, relative to the current treatment approaches, including, for example, sacral nerve stimulation […]<\/p>","protected":false},"featured_media":31463,"template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"\n

Martha Gilbert, Simona \u010caputov\u00e1, Delielena Poli, Manou Kooy, Georgia Sturt, Josephine Parker and Richard M Day.<\/strong><\/p>\n\n\n\n

Cell & Gene Therapy Insights 2023; 9(10), 1293\u20131306.<\/p>\n\n\n\n

Fecal incontinence is a prevalent condition, that remains vastly underreported. The condition impacts the patients\u2019 quality of life and has negative socio-economic and environmental impact on the society. Current patient management guidelines recommend a stepwise approach to treating fecal incontinence, from conservative treatment options, through minimally invasive surgical options, all the way to first- and second-line surgical options. Unfortunately, the conservative treatments remain ineffective, and, in many cases, the surgical options are either not desirable or not suitable. Regenerative medicine, and specifically, cell therapy, has the potential to offer a curative treatment that is less invasive, more effective and efficient. Cell therapy technologies, while still under development, can improve the current state-of-play in the realm of fecal incontinence at the clinical, patient, and socio-economic level. The aim of this article is twofold. Firstly, it is to raise awareness about the silent affliction that fecal incontinence is and about the impact that it has on patients and society. Secondly, it is to position cell therapy, relative to the current treatment approaches, including, for example, sacral nerve stimulation and sphincteroplasty, as to emphasize its potential to provide a suitable treatment alternative. <\/p>\n\n\n\n

Access the full paper here:<\/p>\n\n\n\n

https:\/\/www.insights.bio\/cell-and-gene-therapy-insights\/journal\/article\/3016\/Building-rings-with-spheres-a-cell-therapy-approach-to-incontinence<\/a><\/p>\n","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","_links_to":"","_links_to_target":""},"categories":[43],"class_list":["post-31461","publication","type-publication","status-publish","has-post-thumbnail","hentry","category-publication"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/publication\/31461","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/publication"}],"about":[{"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/types\/publication"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/media\/31463"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/media?parent=31461"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/categories?post=31461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}