{"id":28691,"date":"2020-09-05T00:19:04","date_gmt":"2020-09-05T00:19:04","guid":{"rendered":"https:\/\/amelie-project.eu\/?page_id=28691"},"modified":"2021-01-25T12:42:37","modified_gmt":"2021-01-25T12:42:37","slug":"vision-y-objetivos","status":"publish","type":"page","link":"https:\/\/amelie-project.eu\/es\/vision-y-objetivos\/","title":{"rendered":"Visi\u00f3n y objetivos"},"content":{"rendered":"[et_pb_section fb_built=”1″ admin_label=”Hero section” _builder_version=”4.6.3″ _module_preset=”ac17d3a6-8373-45ed-95ce-70484e82a9b6″ use_background_color_gradient=”off” saved_tabs=”all”][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.6.3″ _module_preset=”default” width=”100%” module_alignment=”left” custom_padding=”|||4%|false|false” custom_padding_tablet=”|||6%|false|false” custom_padding_phone=”|||7%|false|false”][et_pb_column type=”4_4″ _builder_version=”4.6.3″ _module_preset=”default”][dsm_block_reveal_text block_reveal_text=”VISION” heading_html_tag=”h1″ block_reveal_color=”#0e94f9″ block_reveal_delay=”0″ _builder_version=”4.6.3″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”4vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”8vw” header_font_size_phone=”10vw” header_font_size_last_edited=”on|desktop”][\/dsm_block_reveal_text][dsm_block_reveal_text block_reveal_text=”AND OBJECTIVES” block_reveal_color=”#0e94f9″ _builder_version=”4.6.3″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”3vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”5vw” header_font_size_phone=”6vw” header_font_size_last_edited=”on|phone”][\/dsm_block_reveal_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Features” _builder_version=”4.6.3″ background_enable_color=”off” custom_padding=”100px|0px|100px|0px||”][et_pb_row column_structure=”1_3,1_3,1_3″ admin_label=”Sending Payments” _builder_version=”3.25″ max_width=”1440px” custom_margin=”|||” use_custom_width=”on” custom_width_px=”1440px”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/shutterstock_1069097789-Converted-1.png” title_text=”shutterstock_1069097789 %91Converted%93″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.6.3″ animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”10%”][\/et_pb_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_font_size=”16px” text_line_height=”1.8em” header_font=”||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_color=”#000000″ header_2_font_size=”32px” header_2_line_height=”1.3em” header_3_font=”||||||||” header_4_font=”||||||||” text_orientation=”center” hover_enabled=”0″ sticky_enabled=”0″ text_text_color=”#000000″]

Nuestra misi\u00f3n<\/h2>\n

El consorcio propone un enfoque traslacional radical e innovador para fabricar y suministrar al organismo c\u00e9lulas dependientes de anclaje, como una forma de nueva terapia celular, con el fin de establecer terapias de medicina regenerativa m\u00e1s eficaces para la FI y otras indicaciones cl\u00ednicas.<\/p>[\/et_pb_text][et_pb_button button_url=”\/approach\/” button_text=”LEARN MORE” button_alignment=”center” _builder_version=”4.6.3″ _module_preset=”default” custom_button=”on” button_text_size=”12px” button_text_color=”#000000″ button_bg_color=”#ffffff” button_border_width=”1px” button_border_color=”#000000″ button_border_radius=”5px” button_letter_spacing=”2px” button_font=”Gotham kinda bold|600||on|||||” button_icon=”%%20%%” button_icon_color=”#000000″ button_on_hover=”off” custom_margin=”-17px||||false|false” custom_padding=”12px|30px|12px|20px|false|false” animation_style=”fold” animation_duration=”850ms” animation_intensity_fold=”16%” hover_enabled=”0″ button_letter_spacing_tablet=”” button_letter_spacing_phone=”1px” button_letter_spacing_last_edited=”on|phone” button_bg_color__hover=”#0c71c3″ button_bg_color__hover_enabled=”on|desktop” button_border_color__hover=”rgba(0,0,0,0)” button_border_color__hover_enabled=”on|desktop” button_letter_spacing__hover=”2px” button_letter_spacing__hover_enabled=”off|desktop” box_shadow_vertical_button__hover=”8px” box_shadow_vertical_button__hover_enabled=”on|hover” box_shadow_color__hover_enabled=”on|hover” box_shadow_color__hover=”rgba(7,82,140,0.54)” box_shadow_vertical__hover_enabled=”on|desktop” box_shadow_vertical__hover=”10px” button_bg_enable_color__hover=”on” button_text_color__hover_enabled=”on|desktop” button_text_color__hover=”#ffffff” button_border_width__hover_enabled=”on|hover” button_border_width__hover=”1px” button_icon_color__hover_enabled=”on|desktop” button_icon_color__hover=”#ffffff” sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/shutterstock_1289992183-Converted-1.png” title_text=”shutterstock_1289992183 %91Converted%93″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.6.3″ width=”210px” custom_margin=”60px|||” animation_style=”slide” animation_direction=”bottom” animation_delay=”200ms” animation_intensity_slide=”10%” locked=”off”][\/et_pb_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_font_size=”16px” text_line_height=”1.8em” header_font=”||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_color=”#000000″ header_2_font_size=”32px” header_2_line_height=”1.3em” header_3_font=”||||||||” header_4_font=”||||||||” text_orientation=”center” locked=”off” text_text_color=”#000000″ hover_enabled=”0″ sticky_enabled=”0″]

La condici\u00f3n<\/h2>\n

La incontinencia fecal es una enfermedad frecuente. Aunque no pone en peligro la vida, la Organizaci\u00f3n Mundial de la Salud (OMS) la considera una enfermedad que afecta gravemente a la vida diaria y la productividad de las personas afectadas y sus familias, y supone una carga considerable para los servicios sanitarios europeos. Existe una necesidad terap\u00e9utica especialmente insatisfecha para los pacientes con s\u00edntomas graves de incontinencia fecal (IF), que o bien no son aptos para someterse a las opciones quir\u00fargicas disponibles en la actualidad, o bien no desean hacerlo, pero que podr\u00edan beneficiarse de un enfoque m\u00e9dico regenerativo.<\/p>[\/et_pb_text][et_pb_button button_url=”\/our-research\/” button_text=”LEARN MORE” button_alignment=”center” _builder_version=”4.6.3″ _module_preset=”default” custom_button=”on” button_text_size=”12px” button_text_color=”#000000″ button_bg_color=”#ffffff” button_border_width=”1px” button_border_color=”#000000″ button_border_radius=”5px” button_letter_spacing=”2px” button_font=”Gotham kinda bold|600||on|||||” button_icon=”%%20%%” button_icon_color=”#000000″ button_on_hover=”off” custom_margin=”-17px||||false|false” custom_padding=”12px|30px|12px|20px|false|false” animation_style=”fold” animation_duration=”850ms” animation_intensity_fold=”16%” button_letter_spacing_tablet=”” button_letter_spacing_phone=”1px” button_letter_spacing_last_edited=”on|phone” button_bg_color__hover=”#0c71c3″ button_bg_color__hover_enabled=”on|desktop” button_border_color__hover=”rgba(0,0,0,0)” button_border_color__hover_enabled=”on|desktop” button_letter_spacing__hover=”2px” button_letter_spacing__hover_enabled=”on|desktop” box_shadow_vertical_button__hover=”8px” box_shadow_vertical_button__hover_enabled=”on|hover” box_shadow_color__hover_enabled=”on|hover” box_shadow_color__hover=”rgba(7,82,140,0.54)” box_shadow_vertical__hover_enabled=”on|desktop” box_shadow_vertical__hover=”10px” button_text_color__hover=”#ffffff” button_text_color__hover_enabled=”on|desktop” button_border_width__hover=”1px” button_border_width__hover_enabled=”on|hover” button_icon_color__hover=”#ffffff” button_icon_color__hover_enabled=”on|desktop”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/12\/shutterstock_1069097789-Converted.png” title_text=”shutterstock_1069097789 %91Converted%93″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.6.3″ custom_padding=”||||false|false” custom_padding_tablet=”50px||||false|false” custom_padding_phone=”” custom_padding_last_edited=”on|desktop” animation_style=”slide” animation_direction=”bottom” animation_duration=”100ms” animation_intensity_slide=”10%”][\/et_pb_image][et_pb_text _builder_version=”4.6.3″ text_font=”Gotham kinda bold||||||||” text_font_size=”16px” text_line_height=”1.8em” header_font=”||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_color=”#000000″ header_2_font_size=”32px” header_2_line_height=”1.3em” header_3_font=”||||||||” header_4_font=”||||||||” text_orientation=”center” locked=”off” text_text_color=”#000000″]

Nuestra visi\u00f3n<\/h2>\n

AMELIE desarrollar\u00e1 un novedoso producto de ingenier\u00eda tisular (medicamento combinado de terapia avanzada) que comprende la fijaci\u00f3n de las c\u00e9lulas dependientes del anclaje a un microportador implantable biodegradable y cl\u00ednicamente cualificado, con el fin de mejorar directamente los s\u00edntomas cl\u00ednicos de la IF.<\/p>[\/et_pb_text][et_pb_button button_url=”\/engagement-activities\/” button_text=”LEARN MORE” button_alignment=”center” _builder_version=”4.6.3″ _module_preset=”default” custom_button=”on” button_text_size=”12px” button_text_color=”#000000″ button_bg_color=”#ffffff” button_border_width=”1px” button_border_color=”#000000″ button_border_radius=”5px” button_letter_spacing=”2px” button_font=”Gotham kinda bold|600||on|||||” button_icon=”%%20%%” button_icon_color=”#000000″ button_on_hover=”off” custom_margin=”-17px||||false|false” custom_padding=”12px|30px|12px|20px|false|false” animation_style=”fold” animation_duration=”850ms” animation_intensity_fold=”16%” button_letter_spacing_tablet=”” button_letter_spacing_phone=”1px” button_letter_spacing_last_edited=”on|phone” button_bg_color__hover=”#0c71c3″ button_bg_color__hover_enabled=”on|desktop” button_border_color__hover=”rgba(0,0,0,0)” button_border_color__hover_enabled=”on|desktop” button_letter_spacing__hover=”2px” button_letter_spacing__hover_enabled=”on|desktop” box_shadow_vertical_button__hover=”8px” box_shadow_vertical_button__hover_enabled=”on|hover” box_shadow_color__hover_enabled=”on|hover” box_shadow_color__hover=”rgba(7,82,140,0.54)” box_shadow_vertical__hover_enabled=”on|desktop” box_shadow_vertical__hover=”10px” button_text_color__hover=”#ffffff” button_text_color__hover_enabled=”on|desktop” button_border_width__hover=”1px” button_border_width__hover_enabled=”on|hover” button_icon_color__hover=”#ffffff” button_icon_color__hover_enabled=”on|desktop”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Stats and Features” _builder_version=”3.22″ background_color=”#f7f8fc” custom_padding=”80px|0px|54px|0px|false|false”][et_pb_row use_custom_gutter=”on” gutter_width=”4″ _builder_version=”4.6.3″ custom_margin=”||||false|false” custom_padding=”0px|||”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” parallax__hover=”off” parallax_method__hover=”on” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.6.3″ _module_preset=”default” header_font=”Gotham||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_align=”center” header_2_text_color=”#000000″ header_2_font_size=”5vh” header_2_line_height=”1.2em” hover_enabled=”0″ sticky_enabled=”0″]

Objetivos AMELIE<\/h2>[\/et_pb_text][et_pb_blurb title=”Objective 1:” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1093px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” locked=”off” sticky_enabled=”0″]

Establecer nuevos procesos s\u00f3lidos para la fabricaci\u00f3n, caracterizaci\u00f3n, transporte y suministro de microportadores biodegradables e implantables.<\/span><\/p>[\/et_pb_blurb][et_pb_blurb title=”Objective 2:” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” locked=”off” sticky_enabled=”0″]

Demostrar la seguridad de los microportadores ASMDC mediante ensayos no cl\u00ednicos para cumplir los requisitos normativos nacionales y crear un resumen del producto que permita evaluar la tecnolog\u00eda en toda Europa.<\/span><\/p>[\/et_pb_blurb][et_pb_blurb title=”Objective 3:” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1127px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” locked=”off” sticky_enabled=”0″]

Llevar a cabo un ensayo paneuropeo aleatorizado y doble ciego para determinar si los microtransportadores conducen a una reducci\u00f3n de la frecuencia de los episodios de IF.<\/span><\/p>[\/et_pb_blurb][et_pb_blurb title=”Objective 4:” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” locked=”off” sticky_enabled=”0″]

Implicar a las sociedades nacionales y regionales con el apoyo de organizaciones ben\u00e9ficas europeas, redes de apoyo a los pacientes y el p\u00fablico para establecer canales para la actividad de la IPP y la difusi\u00f3n de los avances del proyecto a los pacientes, el p\u00fablico y la comunidad cient\u00edfica.<\/p>[\/et_pb_blurb][et_pb_blurb title=”Objective 5:” url=”#” icon_placement=”left” image_max_width=”64px” content_max_width=”1051px” admin_label=”Chapter” _builder_version=”4.6.3″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|25px|40px|false|false” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” hover_enabled=”0″ box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” locked=”off” sticky_enabled=”0″]

Desarrollar un plan de negocio y una futura estrategia de comercializaci\u00f3n para permitir el acceso de los pacientes a la microportadora en toda Europa y el mundo.<\/span><\/p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.6.3″ _module_preset=”default”][\/et_pb_section]","protected":false},"excerpt":{"rendered":"

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VISI\u00d3N<\/h1><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
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Y OBJETIVOS<\/h2><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Our Mission The consortium proposes a radical, innovative translational approach to manufacture and deliver anchorage-dependent cells into the body, as a form of new cell therapy, to establish more effective regenerative medicine therapies for FI and other clinical indications.The Condition Faecal incontinence is a common condition. Whilst not life threatening, it is classified as a disease by the World Health Organization (WHO), seriously impairing daily living and productivity of affected individuals and their families, and resulting in a substantial burden on European health services. There is a particular therapeutic unmet need for patients with severe symptoms of faecal incontinence (FI), who are either unsuitable for, or do not wish to undergo, currently available surgical options, but who may benefit from a regenerative medical approach.Our Vision AMELIE will develop a novel tissue engineered product (combined advanced therapy medicinal product) that comprises attaching the anchorage dependent cells to an implantable biodegradable, clinically qualified microcarrier so as to directly improve the clinical symptoms of FI.AMELIE ObjectivesEstablish new robust processes for the manufacturing, […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-28691","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/pages\/28691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/comments?post=28691"}],"version-history":[{"count":38,"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/pages\/28691\/revisions"}],"predecessor-version":[{"id":31170,"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/pages\/28691\/revisions\/31170"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/es\/wp-json\/wp\/v2\/media?parent=28691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}