{"id":28691,"date":"2020-09-05T00:19:04","date_gmt":"2020-09-05T00:19:04","guid":{"rendered":"https:\/\/amelie-project.eu\/?page_id=28691"},"modified":"2026-07-01T10:07:51","modified_gmt":"2026-07-01T10:07:51","slug":"vision-und-ziele","status":"publish","type":"page","link":"https:\/\/amelie-project.eu\/de\/vision-und-ziele\/","title":{"rendered":"Vision und Zielsetzungen"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”Hero section” _builder_version=”4.16″ _module_preset=”ac17d3a6-8373-45ed-95ce-70484e82a9b6″ use_background_color_gradient=”off” saved_tabs=”all” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.16″ _module_preset=”default” width=”100%” module_alignment=”left” custom_padding=”|||4%|false|false” custom_padding_tablet=”|||6%|false|false” custom_padding_phone=”|||7%|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][dsm_block_reveal_text block_reveal_text=”VISION” heading_html_tag=”h1″ block_reveal_color=”#0e94f9″ block_reveal_delay=”0″ _builder_version=”4.16″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”4vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”8vw” header_font_size_phone=”10vw” header_font_size_last_edited=”on|desktop” global_colors_info=”{}”][\/dsm_block_reveal_text][dsm_block_reveal_text block_reveal_text=”AND OBJECTIVES” block_reveal_color=”#0e94f9″ _builder_version=”4.16″ _module_preset=”default” header_font=”AMELIE||||||||” header_text_color=”#0e94f9″ header_font_size=”3vw” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”||||false|false” custom_padding_last_edited=”on|phone” header_font_size_tablet=”5vw” header_font_size_phone=”6vw” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/dsm_block_reveal_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Features” _builder_version=”4.16″ background_enable_color=”off” custom_padding=”100px|0px|100px|0px||” global_colors_info=”{}”][et_pb_row column_structure=”1_3,1_3,1_3″ admin_label=”Sending Payments” _builder_version=”4.16″ max_width=”1440px” custom_margin=”|||” use_custom_width=”on” custom_width_px=”1440px” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/10\/shutterstock_1069097789-Converted-1.png” title_text=”shutterstock_1069097789 %91Converted%93″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”10%” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.16″ text_font=”Gotham kinda bold||||||||” text_text_color=”#000000″ text_font_size=”16px” text_line_height=”1.8em” header_font=”||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_color=”#000000″ header_2_font_size=”32px” header_2_line_height=”1.3em” header_3_font=”||||||||” header_4_font=”||||||||” text_orientation=”center” global_colors_info=”{}”]<\/p>\n

Unser Auftrag<\/h2>\n

Das Konsortium leistet Pionierarbeit bei einem neuartigen translationalen Ansatz zur Herstellung und Verabreichung von verankerungsabh\u00e4ngigen Zellen. Da diese Technologie die Implantation von Zellen erm\u00f6glicht, w\u00e4hrend diese an einem tragenden Ger\u00fcst befestigt bleiben, hat sie das Potenzial, Therapien der regenerativen Medizin bei Stuhlinkontinenz und vielen anderen klinischen Anwendungen zu verbessern.<\/span><\/p>\n

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Der ungedeckte Bedarf<\/h2>\n
Von Stuhlinkontinenz sind europaweit mehr als 67 Millionen Menschen betroffen, was ein weit verbreitetes, aber oft untersch\u00e4tztes Problem f\u00fcr die \u00f6ffentliche Gesundheit darstellt.<\/div>\n
Obwohl sie nicht lebensbedrohlich ist, wird sie von der Weltgesundheitsorganisation (WHO) als eine Krankheit eingestuft, die tiefgreifende Auswirkungen auf Lebensqualit\u00e4t, <\/span>Alltagsfunktionen, <\/span>Produktivit\u00e4t und <\/span>Gesundheitssysteme.<\/span><\/div>\n
Trotz der hohen Pr\u00e4valenz sind die derzeitigen Behandlungsm\u00f6glichkeiten nach wie vor begrenzt. Sie sind oft invasiv, nicht f\u00fcr alle Patienten geeignet oder bieten keinen dauerhaften Langzeitnutzen, was zu einem erheblichen ungedeckten klinischen Bedarf f\u00fchrt.<\/div>\n

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Unsere Vision<\/h2>\n

AMELIE entwickelt ein neuartiges Produkt aus dem Bereich des Tissue Engineering, das als kombiniertes Arzneimittel der fortgeschrittenen Therapie eingestuft wird. Dabei werden adh\u00e4sionsabh\u00e4ngige Zellen an einen implantierbaren, biologisch abbaubaren und klinisch qualifizierten Mikrotr\u00e4ger gebunden, mit dem Ziel, die klinischen Symptome der Stuhlinkontinenz direkt zu lindern.<\/span><\/p>\n

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AMELIE Zielsetzungen<\/h2>\n

[\/et_pb_text][et_pb_blurb title=”Objective 1:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1093px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Entwicklung neuer robuster Verfahren f\u00fcr die Herstellung, Charakterisierung, den Transport und die Verabreichung biologisch abbaubarer, implantierbarer Mikrotr\u00e4ger<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 2:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Nachweis der Sicherheit der ASMDC-Mikrotr\u00e4ger durch nichtklinische Tests, um die nationalen Vorschriften zu erf\u00fcllen, und Erstellung einer Produktzusammenfassung, die eine europaweite Bewertung der Technologie erm\u00f6glicht.<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 3:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1127px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Durchf\u00fchrung einer europaweiten randomisierten Doppelblindstudie, um festzustellen, ob die Mikrocarrier zu einer Verringerung der H\u00e4ufigkeit von FI-Episoden f\u00fchren.<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 4:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1400px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|30px|40px” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Einbindung nationaler und regionaler Gesellschaften mit Unterst\u00fctzung europ\u00e4ischer Wohlt\u00e4tigkeitsorganisationen, Patientenunterst\u00fctzungsnetzen und der \u00d6ffentlichkeit, um Kan\u00e4le f\u00fcr PPI-Aktivit\u00e4ten und die Verbreitung von Projektentwicklungen an Patienten, die \u00d6ffentlichkeit und die wissenschaftliche Gemeinschaft zu schaffen.<\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective 5:” url=”#” icon_placement=”left” image_icon_width=”64px” content_max_width=”1051px” admin_label=”Chapter” _builder_version=”4.16″ header_font=”Gotham kinda bold||||||||” header_text_align=”center” header_text_color=”#000000″ header_line_height=”1.5em” body_font=”Gotham kinda bold||||||||” body_text_color=”#000000″ body_font_size=”16px” body_line_height=”1.9em” background_color=”#ffffff” max_width=”1500px” module_alignment=”center” custom_margin=”||30px||false|false” custom_padding=”30px|40px|25px|40px|false|false” animation_style=”zoom” animation_direction=”bottom” animation_intensity_zoom=”20%” animation_starting_opacity=”100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”0px” box_shadow_blur=”60px” box_shadow_color=”rgba(20,8,7,0.08)” image_max_width=”64px” locked=”off” global_colors_info=”{}”]<\/p>\n

Entwicklung eines Gesch\u00e4ftsplans und einer k\u00fcnftigen Vermarktungsstrategie, um Patienten in ganz Europa und weltweit den Zugang zum Mikrocarrier zu erm\u00f6glichen.<\/span><\/p>\n

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VISION<\/h1><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
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UND ZIELE<\/h2><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Our Mission The consortium is pioneering a novel translational approach to the manufacture and delivery of anchorage-dependent cells. By enabling cells to be implanted while remaining attached to a supportive scaffold, this technology has the potential to improve regenerative medicine therapies for faecal incontinence and many other clinical applications.The Unmet Need Faecal incontinence affects more than 67 million people across Europe, representing a common but under-recognised public health challenge. Although not life-threatening, it is classified by the World Health Organisation (WHO) as a disease that can have a profound impact on quality of life, daily functioning, productivity, and healthcare systems. Despite its prevalence, current treatment options remain limited. They are often invasive, not suitable for all patients, or fail to provide durable long-term benefit, creating a significant unmet clinical need.Our Vision AMELIE is developing a novel tissue-engineered product, classified as a combined advanced therapy medicinal product, in which anchorage-dependent cells are attached to an implantable, biodegradable and clinically qualified microcarrier with the aim of directly improving the […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-28691","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/amelie-project.eu\/de\/wp-json\/wp\/v2\/pages\/28691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amelie-project.eu\/de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/amelie-project.eu\/de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amelie-project.eu\/de\/wp-json\/wp\/v2\/comments?post=28691"}],"version-history":[{"count":42,"href":"https:\/\/amelie-project.eu\/de\/wp-json\/wp\/v2\/pages\/28691\/revisions"}],"predecessor-version":[{"id":31779,"href":"https:\/\/amelie-project.eu\/de\/wp-json\/wp\/v2\/pages\/28691\/revisions\/31779"}],"wp:attachment":[{"href":"https:\/\/amelie-project.eu\/de\/wp-json\/wp\/v2\/media?parent=28691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}