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AMELIE (A<\/strong><\/span>nchored M<\/span><\/strong>uscle cel<\/strong><\/span>ls for I<\/strong><\/span>ncontinence<\/span><\/strong>) is an innovative collaborative research project funded by the European Union\u2019s Horizon 2020 Framework Programme.<\/p>\n AMELIE is developing a regenerative therapy using a patient\u2019s own muscle cells to repair damaged or weakened sphincter muscle.<\/p>\n<\/div>\n [\/et_pb_cta][et_pb_button button_url=”#Learn-More” button_text=”LEARN MORE” _builder_version=”4.21.0″ _module_preset=”default” custom_button=”on” button_text_size=”12px” button_text_color=”#ffffff” button_bg_color=”#0076C3″ button_border_width=”0px” button_border_color=”#0c71c3″ button_border_radius=”5px” button_letter_spacing=”2px” button_font=”Gotham kinda bold|600||on|||||” button_icon_color=”rgba(255,255,255,0)” button_on_hover=”off” background_layout=”dark” custom_margin=”0px||0px||false|false” custom_padding=”12px|20px|12px|20px|false|false” 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AMELIE is primarily concerned with the effect of injury to the anal sphincter by childbirth, surgery or trauma. Many such patients are unsuitable for current surgical options. 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There will be opportunities to help shape the research, take part in focus groups and surveys, read materials and assist in patient recruitment to clinical trials.<\/span><\/p>\n [\/et_pb_text][et_pb_button button_url=”\/contact” button_text=”LEARN MORE” button_alignment_tablet=”center” button_alignment_phone=”” button_alignment_last_edited=”on|tablet” _builder_version=”4.27.4″ _module_preset=”b3719a75-4a2e-4427-9fcf-d8c04c1f3982″ button_text_size=”14px” button_font=”Gotham kinda bold|600||on|||||” button_icon=”$||divi||400″ button_on_hover=”on” button_letter_spacing_hover=”1px” locked=”off” global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_button][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” custom_css_main_element=”margin: auto;” global_colors_info=”{}” custom_padding__hover=”|||” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_tablet=”order: 1;” custom_css_main_element_phone=”order: 1;”][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=figrg3PRdO4″ play_icon_color=”#000000″ use_icon_font_size=”on” thumbnail_overlay_color=”rgba(0,0,0,0.6)” _builder_version=”4.21.0″ _module_preset=”default” width=”58vh” width_tablet=”100%” width_phone=”” width_last_edited=”on|desktop” module_alignment=”right” custom_margin=”||||false|false” custom_padding=”||||false|false” module_alignment_tablet=”center” module_alignment_phone=”center” module_alignment_last_edited=”on|phone” global_colors_info=”{}” play_icon_color__hover_enabled=”on|hover” play_icon_color__hover=”#000000″][\/et_pb_video][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2026\/07\/AMELIE-Timeline-updated-220726.png” title_text=”AMELIE Timeline updated 220726″ align=”center” _builder_version=”4.27.4″ _module_preset=”default” border_radii=”on|15px|15px|15px|15px” border_width_top=”18px” border_color_top=”#0C71C3″ box_shadow_style=”preset1″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Testimonial” _builder_version=”4.16″ custom_padding=”28px||101px|||” disabled=”on” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ background_color=”#ffffff” background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”1440px” custom_margin=”3.8%|auto||auto|false|false” custom_padding=”|40px||40px” animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”6%” animation_starting_opacity=”100%” border_radii=”on|15px|15px|15px|15px” border_color_all=”#0076C3″ border_width_top=”18px” border_color_top=”#0076c3″ box_shadow_style=”preset3″ box_shadow_vertical=”39px” box_shadow_blur=”80px” box_shadow_color=”rgba(0,0,0,0.1)” use_custom_width=”on” custom_width_px=”1440px” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_testimonial author=”Diana Davis” job_title=”Happy Buyer” portrait_url=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/09\/portrait-square-07.jpg” quote_icon=”off” _builder_version=”4.16″ body_font=”Lato||on||||||” body_text_color=”#898f99″ body_font_size=”20px” body_line_height=”2em” use_background_color=”off” custom_margin=”||60px|” box_shadow_style_image=”preset3″ box_shadow_color_image=”rgba(0,0,0,0.14)” global_colors_info=”{}”]”Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. 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animation=”off” link_option_url=”\/our-research#faecal-incontinence-about-the-condition” border_radii=”on|15px|15px|15px|15px” border_radii_image=”on|100%|100%|100%|100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_blur=”54px” box_shadow_spread=”-2px” box_shadow_color=”rgba(0,0,0,0.04)” icon_font_size=”40px” use_circle=”on” circle_color=”#0076c3″ global_colors_info=”{}” box_shadow_spread__hover=”13px” box_shadow_spread__hover_enabled=”on|desktop” image_icon_background_color__sticky_enabled=”#424242″ image_icon_background_color__sticky=”#424242″]<\/p>\n Faecal Incontinence: <\/span>About The Condition<\/span><\/p>\n [\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_blurb use_icon=”on” font_icon=”||divi||400″ icon_color=”#ffffff” image_icon_background_color=”#0076c3″ image_icon_width=”40px” _builder_version=”4.16″ header_font=”Gotham kinda bold|||on|||||” header_text_color=”#000000″ header_font_size=”15px” header_letter_spacing=”1px” header_line_height=”1.4em” body_font=”Gotham kinda bold|100|||||||” body_text_color=”#000000″ body_line_height=”1.6em” image_icon_custom_padding=”25px|25px|25px|25px|false|false” text_orientation=”center” height=”280px” height_tablet=”” height_phone=”” height_last_edited=”on|desktop” custom_margin=”|||” custom_padding=”60px|40px|60px|40px” animation=”off” link_option_url=”\/our-research#faecal-incontinence-and-regenerative-medicine” border_radii=”on|15px|15px|15px|15px” border_radii_image=”on|100%|100%|100%|100%” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_blur=”54px” box_shadow_spread=”-2px” box_shadow_color=”rgba(0,0,0,0.04)” icon_font_size=”40px” use_circle=”on” circle_color=”#0076c3″ global_colors_info=”{}” box_shadow_spread__hover_enabled=”on|desktop” box_shadow_spread__hover=”13px” image_icon_background_color__sticky_enabled=”#424242″ image_icon_background_color__sticky=”#424242″]<\/p>\n Faecal Incontinence and Regenerative Medicine<\/span><\/p>\n [\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_blurb use_icon=”on” font_icon=”||divi||400″ icon_color=”#ffffff” image_icon_background_color=”#0076c3″ image_icon_width=”40px” _builder_version=”4.16″ header_font=”Gotham kinda bold|||on|||||” header_text_color=”#000000″ header_font_size=”15px” header_letter_spacing=”1px” header_line_height=”1.4em” body_font=”Gotham kinda bold|100|||||||” body_text_color=”#000000″ body_line_height=”1.6em” image_icon_custom_padding=”25px|25px|25px|25px|false|false” text_orientation=”center” height=”280px” height_tablet=”” height_phone=”” height_last_edited=”on|tablet” custom_margin=”|||” custom_padding=”60px|40px|60px|40px” animation=”off” link_option_url=”\/our-research#why-are-conventional-methods-not-working” 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These cells are attached to biodegradable microcarriers, which:<\/div>\n\n
\n\nAMELIE brings together 13 partner organisations from nine countries, combining expertise from academia, healthcare, industry, and research to develop new treatments for people living with faecal incontinence.<\/div>\n<\/div>\nThe project is coordinated by University College London (UCL) and led by Professor Richard Day, Professor of Regenerative Medicine Technology at UCL<\/div>\nCan cell therapy restore muscle function?<\/h3>\n
Our Partners<\/h3>\n
Our Research<\/h3>\n
The AMELIE project brings together a highly interdisciplinary consortium of experts to develop a novel regenerative intervention using autologous skeletal muscle-derived cells to restore sphincter muscle function. In this approach, autologous skeletal muscle-derived cells are attached to implantable microcarriers to enhance cell delivery and engraftment in patients with faecal incontinence.<\/div>\nThe therapy will be evaluated in a randomised clinical trial. It is anticipated that this strategy will improve cell viability, increase the likelihood of muscle regeneration, and ultimately contribute to improved continence outcomes.<\/div>\nGet Involved<\/h3>\n
\n[\/et_pb_testimonial][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_testimonial author=”Jessica Bowen” job_title=”Happy Renter” portrait_url=”https:\/\/amelie-project.eu\/wp-content\/uploads\/2020\/09\/portrait-square-08.jpg” quote_icon=”off” _builder_version=”4.16″ body_font=”Lato||on||||||” body_text_color=”#898f99″ body_font_size=”20px” body_line_height=”2em” use_background_color=”off” custom_margin=”||60px|” box_shadow_style_image=”preset3″ box_shadow_color_image=”rgba(0,0,0,0.14)” locked=”off” global_colors_info=”{}”]”Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.
\n[\/et_pb_testimonial][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Features” _builder_version=”4.16″ custom_padding=”80px|0px|80px|0px|false|false” disabled=”on” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ custom_margin=”|||” custom_padding=”0px||0px|||” border_color_all=”#0076C3″ border_color_top=”#0076c3″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Gotham kinda bold||||||||” text_font_size=”16px” text_line_height=”1.8em” header_font=”||||||||” header_2_font=”Gotham kinda bold||||||||” header_2_text_color=”#000000″ header_2_font_size=”32px” header_2_line_height=”1.5em” header_3_font=”Gotham kinda bold||||||||” text_orientation=”center” max_width=”800px” module_alignment=”center” locked=”off” global_colors_info=”{}”]<\/p>\nThe Science Behind AMELIE<\/h2>\n
Ready to get started?<\/h2>\n
Ready to learn more?<\/h2>\n
Ready to get started?<\/h2>\n
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\tAMELIE<\/h1><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>AMELIE (Anchored Muscle cells for Incontinence) er et innovativt forskningssamarbejde, der finansieres af Den Europ\u00e6iske Unions rammeprogram \u00bbHorizon 2020\u00ab. AMELIE udvikler en regenerativ behandling, hvor patientens egne muskelceller anvendes til at reparere beskadigede eller sv\u00e6kkede lukkemuskler.
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t![\"\"](\"https:\/\/amelie-project.eu\/wp-content\/uploads\/2026\/07\/amelie-cells.jpg\" "\\"amelie-celler\\"")
<\/span>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Hvad vi g\u00f8r: Levering af langvarig, minimalt invasiv celleterapi. Disse celler er fastgjort til biologisk nedbrydelige mikrob\u00e6rere, som: underst\u00f8tter cellernes overlevelse fremmer v\u00e6vsregenerering forbedrer leveringen af behandlingen til det ber\u00f8rte omr\u00e5de. Ved at udnytte kroppens naturlige evne til at reparere sig selv sigter AMELIE mod at tilbyde en langvarig, minimalt invasiv behandling af f\u00e6kal inkontinens. Teknologien har ogs\u00e5 potentielle anvendelsesmuligheder ved andre muskelskader og lidelser ud over tarmhelbredet. AMELIE samler 13 partnerorganisationer fra ni lande og kombinerer ekspertise fra den akademiske verden, sundhedssektoren, industrien og forskningen for at udvikle nye behandlinger til mennesker, der lever med f\u00e6kal inkontinens. Projektet koordineres af University College London (UCL) og ledes af professor Richard Day, professor i regenerativ medicinteknologi ved UCL.\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t![\"\"](\"https:\/\/amelie-project.eu\/wp-content\/uploads\/2026\/02\/05-VC-Cafe-London-260226-Copy-1080x675.jpg\")
\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tRepr\u00e6sentant for AMELIE-projektet ved Cleveland Clinic Surgical Innovation Summit 2026<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/h2>\n\t\t\t\t\t\t\t\t<\/header>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t